Description |
SUFU negative regulator of hedgehog signaling |
leucine zipper tumor suppressor 1 |
Image |
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No pdb structure |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Adult body size ( 32376654)
- Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359)
- Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359)
- Allergy ( 27182965)
- Autism spectrum disorder or schizophrenia ( 28540026)
- Body mass index ( 25673413 28448500)
- Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
- Body mass index in physically active individuals ( 28448500)
- Brain morphology (MOSTest) ( 32665545)
- Creatinine levels ( 29403010)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- Eosinophil counts ( 32888494)
- Estimated glomerular filtration rate ( 30604766)
- Glomerular filtration rate ( 29403010)
- Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
- Height ( 28552196)
- Nickel levels ( 26025379)
- Optic disc size ( 31809533)
- Platelet count ( 32888494)
- Prostate cancer ( 23535732)
- Refractive error ( 32231278)
- Sum eosinophil basophil counts ( 27863252)
- Systolic blood pressure ( 30578418)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for body mass index ( 25673412)
- Waist-to-hip ratio adjusted for BMI ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- White blood cell count ( 29403010)
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Interacting Genes |
50 interacting genes:
ABI3
BFSP2
BTRC
CRTC2
CRX
DISC1
FBXL17
FXR1
GLI1
GLI2
GLI3
GLIS3
HDX
HMGA1
HNRNPA1
ITCH
KRT27
KRT75
L3MBTL3
LAMTOR3
LCA5
LGALS3
LZTS1
MAGEL2
MEOX2
MID1IP1
NCOA3
PEX26
PIAS1
QPRT
RBPJ
RCN3
RNF19A
SAP18
SETDB1
SH3RF1
SLC41A3
STK36
STX19
TLE5
UBE2D1
ZIC1
ZNF114
ZNF219
ZNF263
ZNF330
ZNF446
ZNF763
ZNF764
ZSCAN18
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100 interacting genes:
AGTR1
AMOT
AP1M1
BYSL
CARD9
CCDC102B
CCDC120
CCDC13
CCDC187
CCDC57
CCHCR1
CDC23
CDC25C
CDC37
CDC7
CDK1
CEP83
CKS1B
COG2
COPB1
CWF19L2
DDX6
EEF1G
ELOA
ENKD1
EXOC8
FAM161A
FAM161B
FAM50B
FAM71F1
FAM81B
FAM90A1
GAS8
GOLGA1
GPKOW
HMGB2
IDO2
KANK2
KAT5
KAZN
KDM1A
KIF9
KIFC3
LENG1
LMNB2
LMO1
LMO2
LMO3
LMO4
LNX1
LSM2
MAPK9
MCRS1
METTL21A
MFAP1
MID2
NEK6
NTAQ1
PIBF1
PICK1
PLEKHA7
POLR1C
POLR3C
PPP1R18
PRKAB2
PRPF18
PRPF3
PSMA1
PSPC1
QARS1
RABIF
RHPN1
RSPH14
RUNX1T1
SCNM1
SGF29
SOGA1
SPDYC
SUFU
SYT17
SYT6
SYTL4
TBC1D1
TBC1D7
TCEA2
TSGA10
TSGA10IP
TTC9C
TXLNA
TXLNB
TXNDC9
UBASH3A
ZGPAT
ZMYND19
ZNF250
ZNF3
ZNF35
ZNF417
ZNF572
ZNF587
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Entrez ID |
51684 |
11178 |
HPRD ID |
06124 |
05945 |
Ensembl ID |
ENSG00000107882
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ENSG00000061337
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Uniprot IDs |
A0A223LX15
Q9UMX1
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Q9Y250
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PDB IDs |
1M1L
4BL8
4BL9
4BLA
4BLB
4BLD
4KM8
4KM9
4KMD
4KMH
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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