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TDP2 and WBP2
Data Source:
BioGRID
(two hybrid)
TDP2
WBP2
Description
tyrosyl-DNA phosphodiesterase 2
WW domain binding protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Aggresome
Nuclear Body
PML Body
Chromatin
Nucleus
Cytoplasm
Molecular Function
Magnesium Ion Binding
Single-stranded DNA Binding
Transcription Corepressor Activity
Nuclease Activity
Protein Binding
Manganese Ion Binding
Tyrosyl-RNA Phosphodiesterase Activity
5'-tyrosyl-DNA Phosphodiesterase Activity
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Transcription Coactivator Activity
Protein Binding
Estrogen Receptor Binding
Chromatin DNA Binding
Biological Process
Double-strand Break Repair
Cell Surface Receptor Signaling Pathway
Viral Process
Negative Regulation Of Transcription, DNA-templated
Neuron Development
Nucleic Acid Phosphodiester Bond Hydrolysis
Response To Progesterone
Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Response To Estrogen
Establishment Of Protein Localization
Positive Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Progesterone Receptor Signaling Pathway
Cellular Response To Estrogen Stimulus
Positive Regulation Of Histone H3-K14 Acetylation
Pathways
Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS
Colorectal or endometrial cancer (
26621817
)
Adult body size (
32376654
)
Platelet count (
32888494
)
Red blood cell count (
32888494
)
White matter hyperintensities (
32358547
)
Interacting Genes
35 interacting genes:
AKAP9
ATP5MC2
ATXN1
BLK
BTBD2
C2orf88
CD40
DLX3
DVL2
EPS8
ETS1
ETS2
FLI1
GOLGA2
JAM2
MAPK6
PSEN1
RAB11A
SKIL
SMAD3
SNX13
SRPK2
SUMO1
SUMO2
SUMO3
TAP1
TFIP11
TNFRSF1B
TNFRSF8
TRAF2
TRAF3
TRAF5
TRAF6
UBE2I
WBP2
54 interacting genes:
ANAPC1
ANKRD13A
ANKRD13D
ARCN1
BAG3
CCT7
CLEC4G
COPA
COPB1
COPB2
COPE
COPG1
CUEDC1
DDX17
EEF1B2
EPN2
ESR1
GRPEL1
H4C1
HOMER3
HUWE1
ITCH
KRT18
KRT8
KRT9
LGALS8
MAGEA4
MAGI1
MYO6
NEDD4
NEDD4L
PAX8
POLH
RHBDD3
RNF168
RPS27A
RPS3
SDHA
SEPTIN3
SMAD5
TDP2
TOLLIP
TOM1L2
UBA52
UBC
UBE2D3
UBE2E3
UBE3A
UBQLN1
UIMC1
WWP1
WWP2
WWTR1
YAP1
Entrez ID
51567
23558
HPRD ID
05771
06097
Ensembl ID
ENSG00000111802
ENSG00000132471
Uniprot IDs
A0A384MDM5
O95551
A0A024R8L1
Q969T9
PDB IDs
5INO
5J3P
5J3S
6Q00
6Q01
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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