DDX41 and KLC2

Data Source:
BioGRID (two hybrid)

		DDX41	KLC2
Description		DEAD-box helicase 41	kinesin light chain 2
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GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Cytosol Membrane Catalytic Step 2 Spliceosome	Nucleoplasm Mitochondrion Cytosol Kinesin Complex Microtubule Plasma Membrane Membrane Kinesin I Complex Protein-containing Complex
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding Metal Ion Binding	Protein Binding Kinesin Binding Cadherin Binding
	Biological Process	MRNA Splicing, Via Spliceosome Apoptotic Process Cell Population Proliferation Cell Differentiation Positive Regulation Of Type I Interferon Production	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		STING mediated induction of host immune responses Regulation of innate immune responses to cytosolic DNA IRF3-mediated induction of type I IFN	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Bipolar disorder ( 21926972 31043756) Metabolite levels ( 23823483)
Interacting Genes		7 interacting genes: AIDA CEP70 CHAF1A KLC2 NKAPL SIAH1 TUBG1	16 interacting genes: AIMP2 APP CLSTN1 COIL DDX41 KIF2A KLC1 KLC4 LRRK2 MAPK8IP3 PIK3R3 PRC1 S100A8 YWHAG YWHAQ YWHAZ
Entrez ID		51428	64837
HPRD ID		10490	13917
Ensembl ID		ENSG00000183258	ENSG00000174996
Uniprot IDs		B3KRK2 Q9UJV9	Q9H0B6
PDB IDs		2P6N 5GVR 5GVS 5H1Y	3CEQ 3EDT
Enriched GO Terms of Interacting Partners?
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