DDX41 and CHAF1A

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		DDX41	CHAF1A
Description		DEAD-box helicase 41	chromatin assembly factor 1 subunit A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Cytosol Membrane Catalytic Step 2 Spliceosome	Chromatin Nucleus Protein-containing Complex CAF-1 Complex
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding Metal Ion Binding	Chromatin Binding Protein Binding Identical Protein Binding Unfolded Protein Binding Chromo Shadow Domain Binding
	Biological Process	MRNA Splicing, Via Spliceosome Apoptotic Process Cell Population Proliferation Cell Differentiation Positive Regulation Of Type I Interferon Production	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly
Pathways		STING mediated induction of host immune responses Regulation of innate immune responses to cytosolic DNA IRF3-mediated induction of type I IFN
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		7 interacting genes: AIDA CEP70 CHAF1A KLC2 NKAPL SIAH1 TUBG1	47 interacting genes: ANP32A ANP32B ASF1A ASF1B BLM CBX1 CBX5 CDC7 CDK2 CHAF1B CREBBP DBF4 DDX41 H3-4 H3C6 HMGB2 LZTR1 MBD1 MEI4 MSH6 NOTO PABPC1 PAX6 PCBD2 PCNA POU6F2 RBFOX2 REL SERTAD1 SET SPOP STAT5B SUMO1 SUMO2 SUMO3 TCERG1 TCF4 TRIB3 TRIM28 XRCC5 XRCC6 YWHAB YWHAE YWHAG YWHAQ ZNF408 ZNF620
Entrez ID		51428	10036
HPRD ID		10490	03148
Ensembl ID		ENSG00000183258	ENSG00000167670
Uniprot IDs		B3KRK2 Q9UJV9	Q13111
PDB IDs		2P6N 5GVR 5GVS 5H1Y
Enriched GO Terms of Interacting Partners?
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