KLC2 and KIF2A

Data Source:
HPRD (in vivo)

		KLC2	KIF2A
Description		kinesin light chain 2	kinesin family member 2A
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol Kinesin Complex Microtubule Plasma Membrane Membrane Kinesin I Complex Protein-containing Complex	Spindle Pole Nucleoplasm Nucleolus Cytoplasm Centrosome Centriole Spindle Cytosol Kinesin Complex Microtubule Spindle Microtubule Membrane Nuclear Body Centriolar Subdistal Appendage
	Molecular Function	Protein Binding Kinesin Binding Cadherin Binding	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Microtubule Cytoskeleton Organization Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Microtubule Depolymerization Mitotic Spindle Organization Nervous System Development Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cell Differentiation Regulation Of Cell Migration Cell Division Mitotic Spindle Assembly
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Metabolite levels ( 23823483)	Diastolic blood pressure ( 30224653) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		16 interacting genes: AIMP2 APP CLSTN1 COIL DDX41 KIF2A KLC1 KLC4 LRRK2 MAPK8IP3 PIK3R3 PRC1 S100A8 YWHAG YWHAQ YWHAZ	13 interacting genes: CASK CLSTN1 DYNLT1 FAM13C FXR2 H3-4 KLC1 KLC2 LARP1B LMO2 LMO3 MRPL53 SUMO2
Entrez ID		64837	3796
HPRD ID		13917	03996
Ensembl ID		ENSG00000174996	ENSG00000068796
Uniprot IDs		Q9H0B6	A0A6Q8PFA6 B0AZS5 O00139
PDB IDs		3CEQ 3EDT	2GRY 6BBN
Enriched GO Terms of Interacting Partners?
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