KLC2 and PRC1

Data Source:
BioGRID (two hybrid)

		KLC2	PRC1
Description		kinesin light chain 2	protein regulator of cytokinesis 1
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol Kinesin Complex Microtubule Plasma Membrane Membrane Kinesin I Complex Protein-containing Complex	Spindle Pole Nucleus Nucleoplasm Chromosome Cytoplasm Spindle Cytosol Spindle Microtubule Plasma Membrane Microtubule Cytoskeleton Midbody Intercellular Bridge Contractile Ring Mitotic Spindle Midzone
	Molecular Function	Protein Binding Kinesin Binding Cadherin Binding	Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Mitotic Spindle Elongation Microtubule Cytoskeleton Organization Microtubule Bundle Formation Positive Regulation Of Cell Population Proliferation Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly Cell Division
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	RHO GTPases activate CIT
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Metabolite levels ( 23823483)	Breast cancer ( 29059683 25038754) Mean platelet volume ( 32888494 27863252) Multisite chronic pain ( 31194737) Red cell distribution width ( 32888494) Type 2 diabetes ( 22885922 24509480 30054458 30297969 26818947 32499647 20581827 30718926 28869590)
Interacting Genes		16 interacting genes: AIMP2 APP CLSTN1 COIL DDX41 KIF2A KLC1 KLC4 LRRK2 MAPK8IP3 PIK3R3 PRC1 S100A8 YWHAG YWHAQ YWHAZ	29 interacting genes: AKAP9 CASK CCDC85B CCNA2 CCNB1 CCNE1 CDK1 CDK2 CINP FXR2 KIF3B KIF4A KLC2 KLC4 KRT20 MAT2A NDEL1 PCM1 PKIA PLK1 RACGAP1 RBM10 RPA2 SF3B2 SLAIN1 SUMO2 TRIM37 USHBP1 YWHAE
Entrez ID		64837	9055
HPRD ID		13917	17899
Ensembl ID		ENSG00000174996	ENSG00000198901
Uniprot IDs		Q9H0B6	A0A024RC67 O43663
PDB IDs		3CEQ 3EDT	3NRX 3NRY 4L3I 4L6Y 5KMG
Enriched GO Terms of Interacting Partners?
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