DDX41 and AIDA

Data Source:
BioGRID (two hybrid)

		DDX41	AIDA
Description		DEAD-box helicase 41	axin interactor, dorsalization associated
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Cytosol Membrane Catalytic Step 2 Spliceosome	Cellular_component Cytoplasm Membrane
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding Metal Ion Binding	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding
	Biological Process	MRNA Splicing, Via Spliceosome Apoptotic Process Cell Population Proliferation Cell Differentiation Positive Regulation Of Type I Interferon Production	Dorsal/ventral Pattern Formation Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of JUN Kinase Activity Negative Regulation Of JNK Cascade Determination Of Ventral Identity
Pathways		STING mediated induction of host immune responses Regulation of innate immune responses to cytosolic DNA IRF3-mediated induction of type I IFN
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Coronary artery disease ( 29212778)
Interacting Genes		7 interacting genes: AIDA CEP70 CHAF1A KLC2 NKAPL SIAH1 TUBG1	10 interacting genes: APP DDIT4L DDX41 EMSY FAM118A LNX1 PINX1 PLEKHF2 RPL36A ZDHHC17
Entrez ID		51428	64853
HPRD ID		10490	07798
Ensembl ID		ENSG00000183258	ENSG00000186063
Uniprot IDs		B3KRK2 Q9UJV9	Q96BJ3
PDB IDs		2P6N 5GVR 5GVS 5H1Y
Enriched GO Terms of Interacting Partners?
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