BPIFA1 and TIAL1

Data Source:
BioGRID (two hybrid)

		BPIFA1	TIAL1
Description		BPI fold containing family A member 1	TIA1 cytotoxic granule associated RNA binding protein like 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Nucleus Nucleoplasm Cytoplasm Lysosome Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	Molecular_function Protein Binding Lipid Binding	DNA Binding RNA Binding
	Biological Process	Immune Response In Nasopharyngeal-associated Lymphoid Tissue Antimicrobial Humoral Response Antibacterial Humoral Response Innate Immune Response Regulation Of Liquid Surface Tension Multicellular Organismal Water Homeostasis Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Regulation Of Sodium Ion Transmembrane Transport	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Defense Response Fibroblast Growth Factor Receptor Signaling Pathway
Pathways		Antimicrobial peptides	FGFR2 alternative splicing
Drugs
Diseases
GWAS			Depressive symptoms (stressful life events interaction) ( 27529621) Monocyte percentage of white cells ( 32888494) Parkinson's disease ( 27182965) Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) ( 27047539)
Interacting Genes		50 interacting genes: ALKBH4 COL8A1 CRYBA2 CSKMT DUSP21 ELK3 EML2 FAAP20 FAM222B GADD45GIP1 GCA HCK HNF1B HOXB9 HSFY1 HSFY2 INCA1 INIP KIR2DL4 KRT3 LNX1 MEIS2 MKRN3 MTIF3 NPAS2 NUP54 PATZ1 PEF1 PITX1 PPIH PRR35 PSMB1 RAMAC RSPH14 RTP5 RUSC1 SAMD11 SIRPB1 SNRNP25 TCF7L2 TEPSIN TFG TIAL1 TLE5 TLX3 UBQLN1 UBQLN2 UBQLN4 VPS25 ZNF765	39 interacting genes: AKAP8L AOC1 BPIFA1 C10orf55 CAMK2A CELF4 DAZAP2 FAM168A FAM168B FUBP1 GRINA INCA1 KLF1 KRTAP8-1 MAGED1 MAPK1 MAPK1IP1L MBNL2 MIR106A MIR106B MIR145 MIR199A1 MIR20A MIR29A MIR29C MIR34A MIR9-2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBPMS2 SMN1 SMN2 SNRPA VPS37C
Entrez ID		51297	7073
HPRD ID		07594	04563
Ensembl ID		ENSG00000198183	ENSG00000151923
Uniprot IDs		Q9NP55	Q01085 Q49AS9
PDB IDs		4KEG 4KGH 4KGO 4N4X 5I7J 5I7K 5I7L	1X4G 2CQI 2DH7
Enriched GO Terms of Interacting Partners?
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