BPIFA1 and KIR2DL4

Data Source:
BioGRID (two hybrid)

		BPIFA1	KIR2DL4
Description		BPI fold containing family A member 1	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Plasma Membrane Membrane Early Endosome Membrane
	Molecular Function	Molecular_function Protein Binding Lipid Binding	Transmembrane Signaling Receptor Activity Protein Binding MHC Class Ib Receptor Activity
	Biological Process	Immune Response In Nasopharyngeal-associated Lymphoid Tissue Antimicrobial Humoral Response Antibacterial Humoral Response Innate Immune Response Regulation Of Liquid Surface Tension Multicellular Organismal Water Homeostasis Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Regulation Of Sodium Ion Transmembrane Transport	Positive Regulation Of Natural Killer Cell Cytokine Production Cellular Defense Response Signal Transduction Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Positive Regulation Of Cellular Senescence
Pathways		Antimicrobial peptides	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS			Objective response to lithium treatment ( 26503763)
Interacting Genes		50 interacting genes: ALKBH4 COL8A1 CRYBA2 CSKMT DUSP21 ELK3 EML2 FAAP20 FAM222B GADD45GIP1 GCA HCK HNF1B HOXB9 HSFY1 HSFY2 INCA1 INIP KIR2DL4 KRT3 LNX1 MEIS2 MKRN3 MTIF3 NPAS2 NUP54 PATZ1 PEF1 PITX1 PPIH PRR35 PSMB1 RAMAC RSPH14 RTP5 RUSC1 SAMD11 SIRPB1 SNRNP25 TCF7L2 TEPSIN TFG TIAL1 TLE5 TLX3 UBQLN1 UBQLN2 UBQLN4 VPS25 ZNF765	9 interacting genes: BPIFA1 FCER1G FHL5 HLA-G INCA1 RBPMS RNF216 TIMMDC1 TRIP6
Entrez ID		51297	3805
HPRD ID		07594	16082
Ensembl ID		ENSG00000198183	ENSG00000189013
Uniprot IDs		Q9NP55	A0A0B4J1S6 A0A376A929 Q99706
PDB IDs		4KEG 4KGH 4KGO 4N4X 5I7J 5I7K 5I7L	3WYR
Enriched GO Terms of Interacting Partners?
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