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POLR1D and PXN
Data Source:
BioGRID
(two hybrid)
POLR1D
PXN
Description
RNA polymerase I and III subunit D
paxillin
Image
No pdb structure
GO Annotations
Cellular Component
RNA Polymerase III Complex
RNA Polymerase I Complex
Stress Fiber
Cytosol
Microtubule Associated Complex
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Cell Cortex
Lamellipodium
Molecular Function
DNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Protein Dimerization Activity
Transcription Coregulator Activity
Protein Binding
Beta-catenin Binding
Vinculin Binding
Protein Phosphatase Binding
Neuropilin Binding
Metal Ion Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Muscle Contraction
Cell Adhesion
Cell-matrix Adhesion
Signal Transduction
Signal Complex Assembly
Transforming Growth Factor Beta Receptor Signaling Pathway
Substrate Adhesion-dependent Cell Spreading
Cellular Response To Reactive Oxygen Species
Endothelial Cell Migration
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Stress Fiber Assembly
Growth Hormone Receptor Signaling Pathway
Pathways
Cytosolic sensors of pathogen-associated DNA
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase III Chain Elongation
RNA Polymerase I Transcription Termination
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
GAB1 signalosome
VEGFA-VEGFR2 Pathway
Smooth Muscle Contraction
Localization of the PINCH-ILK-PARVIN complex to focal adhesions
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
Drugs
Diseases
Treacher Collins syndrome
GWAS
Body mass index (
26426971
)
Bipolar disorder (
31043756
)
Mean spheric corpuscular volume (
32888494
)
Platelet count (
29403010
)
Interacting Genes
15 interacting genes:
CDC25A
CRKL
DDIT3
DNAJB4
DNAJB6
E2F4
GRB2
HAX1
MAGEA11
MRPL12
NFKBIB
NR3C1
POLR1C
POLR1G
PXN
87 interacting genes:
ABL1
ACO1
AHCY
AR
ARHGEF7
ASAP1
ASAP2
BCAR1
BCL2
BLK
CASP3
CEACAM1
CLTC
CREB3L2
CRK
CRKL
CSK
DGUOK
DPY30
EPHB1
FYN
GART
GIT1
GIT2
GRB2
GSK3A
GSK3B
GSN
HDAC6
ILK
ITGA4
ITGA6
ITGA9
ITGAV
ITGB1
ITGB3
LCK
LIMK1
LMO1
LMO3
MAPK1
MAPK3
MAPK8
MATK
NCK1
NEDD9
NF2
PABPC1
PAK1
PAK3
PARVA
PDPK1
PKD1
PLEKHH2
PLEKHN1
POLR1D
PPP2CA
PPP2R5C
PTEN
PTK2
PTK2B
PTPN11
PTPN12
PTPRH
RASA1
REPS2
RHOU
RNF5
SDC4
SELE
SH3RF1
SORBS1
SRC
SYK
TCEANC
TGM2
TLN1
TRIM15
TRIP6
TUBA1B
TUBA3C
TUBA8
TUBG1
TUBG2
VCL
WHRN
YES1
Entrez ID
51082
5829
HPRD ID
17877
03937
Ensembl ID
ENSG00000186184
ENSG00000089159
Uniprot IDs
A0A087WTY1
P0DPB5
P0DPB6
A0A140VJQ8
P49023
PDB IDs
1KKY
1KL0
1OW6
1OW7
1OW8
2K2R
2O9V
2VZD
2VZG
2VZI
3GM1
3PY7
3RQE
3RQF
3RQG
3U3F
4EDN
4R32
4XGZ
4XH2
5UWH
6IUI
6PW8
6U4M
6U4N
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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