COQ8A and ABHD5

Data Source:
BioGRID (two hybrid)

		COQ8A	ABHD5
Description		coenzyme Q8A	abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Integral Component Of Membrane Extrinsic Component Of Mitochondrial Inner Membrane	Nucleoplasm Mitochondrion Lipid Droplet Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Kinase Activity ADP Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Triglyceride Lipase Activity Protein Binding Lysophosphatidic Acid Acyltransferase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation	Fatty Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Negative Regulation Of Sequestering Of Triglyceride Positive Regulation Of Triglyceride Catabolic Process Cell Differentiation Positive Regulation Of Lipoprotein Lipase Activity Lipid Homeostasis
Pathways			Triglyceride catabolism
Drugs		Fostamatinib
Diseases		Coenzyme Q10 deficiency Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)	Dorfman-Chanarin syndrome; Chanarin-Dorfman syndrome
GWAS			General risk tolerance (MTAG) ( 30643258) Inflammatory skin disease ( 25574825)
Interacting Genes		26 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM159 TMEM239 TPD52L2	21 interacting genes: CERCAM COQ8A DGAT2L6 GAD2 GET1 GRIA4 MIEF1 PCNX2 PLIN1 PLIN2 PLIN3 PNPLA2 RBFA RNF24 RUSC1 SH3GLB1 SLC44A3 TMEM14B TMEM31 TPD52L2 ZCCHC12
Entrez ID		56997	51099
HPRD ID		07375	11986
Ensembl ID		ENSG00000163050	ENSG00000011198
Uniprot IDs		Q8NI60	A0A0S2Z5D6 Q8WTS1
PDB IDs		4PED 5I35
Enriched GO Terms of Interacting Partners?
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