COQ8A and MAL2

Data Source:
BioGRID (two hybrid)

		COQ8A	MAL2
Description		coenzyme Q8A	mal, T cell differentiation protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Integral Component Of Membrane Extrinsic Component Of Mitochondrial Inner Membrane	Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Kinase Activity ADP Binding	Protein Binding Structural Constituent Of Myelin Sheath
	Biological Process	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation	Myelination Transcytosis
Pathways
Drugs		Fostamatinib
Diseases		Coenzyme Q10 deficiency Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS			Blood pressure (smoking interaction) ( 25189868) Gallstone disease ( 30504769) Hippocampal atrophy ( 19668339) Osteoprotegerin levels ( 25080503)
Interacting Genes		26 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM159 TMEM239 TPD52L2	49 interacting genes: ABCG8 AQP6 ARFIP2 ARL13B ATP6V0E1 CD160 CD68 COQ8A CREB3 CREB3L1 ECPAS FAM3A GAD1 GAD2 GJB1 GPR152 HSFX1 HSFX2 MRM1 MTERF3 MUC1 NDRG4 NFAM1 PBX3 PIMREG PITPNC1 POLL PPP1CA PTPN9 RAB37 REEP4 RETREG3 S100B SCN3B SGK1 SH3GL1 SH3GLB1 SHMT2 SLC35C2 SUCLA2 TBRG4 THAP4 TMEM14B TPD52 TPD52L1 TPD52L2 TTPA TUBB VARS2
Entrez ID		56997	114569
HPRD ID		07375	14351
Ensembl ID		ENSG00000163050	ENSG00000147676
Uniprot IDs		Q8NI60	A0A024R9E4 Q969L2
PDB IDs		4PED 5I35
Enriched GO Terms of Interacting Partners?
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