COQ8A and STX10

Data Source:
BioGRID (two hybrid)

		COQ8A	STX10
Description		coenzyme Q8A	syntaxin 10
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GO Annotations	Cellular Component	Mitochondrion Integral Component Of Membrane Extrinsic Component Of Mitochondrial Inner Membrane	Trans-Golgi Network Cytosol Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane SNARE Complex Vesicle Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Kinase Activity ADP Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation	Intracellular Protein Transport Vesicle Fusion Regulation Of Protein Localization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Vesicle Docking
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs		Fostamatinib
Diseases		Coenzyme Q10 deficiency Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS			Venous thromboembolism ( 31420334)
Interacting Genes		26 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM159 TMEM239 TPD52L2	5 interacting genes: COQ8A CXorf66 STX1A STX4 TMEM101
Entrez ID		56997	8677
HPRD ID		07375	04791
Ensembl ID		ENSG00000163050	ENSG00000104915
Uniprot IDs		Q8NI60	O60499 Q5U8S2 X6R2W0
PDB IDs		4PED 5I35	4DND
Enriched GO Terms of Interacting Partners?
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