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BCL2L2 and S100B
Data Source:
BioGRID
(two hybrid)
BCL2L2
S100B
Description
BCL2 like 2
S100 calcium binding protein B
Image
GO Annotations
Cellular Component
Mitochondrial Outer Membrane
Bcl-2 Family Protein Complex
Ruffle
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Disordered Domain Specific Binding
Calcium Ion Binding
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Protein Homodimerization Activity
S100 Protein Binding
Tau Protein Binding
Calcium-dependent Protein Binding
RAGE Receptor Binding
Biological Process
Spermatogenesis
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Negative Regulation Of Apoptotic Process
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Axonogenesis
Central Nervous System Development
Learning Or Memory
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Pathways
Nuclear signaling by ERBB4
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
Advanced glycosylation endproduct receptor signaling
Advanced glycosylation endproduct receptor signaling
TRAF6 mediated NF-kB activation
Drugs
Navitoclax
Olopatadine
Calcium
N-Formylmethionine
Arundic acid
(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide
2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Diseases
GWAS
Height (
28552196
)
Cerebrospinal fluid t-tau:AB1-42 ratio (
28641921
)
Lymphocyte counts (
22286170
)
Interacting Genes
53 interacting genes:
ANKS6
APOC1
APOC2
APOC4
ATP5PF
BAD
BAK1
BAX
BBC3
BCL2L11
BHLHA9
BID
BIK
BMF
BNIP3
BNIP5
C10orf67
CD79A
CHODL
CIDEB
CISD2
CLDN7
ERVFRD-1
FATE1
G0S2
GORAB
GPR151
GPX8
HRK
KASH5
KCNJ6
LMNA
LRRIQ1
MGST2
MUC1
PANX1
PPP1CA
PSCA
RHBDD2
S100B
SAR1A
SGPL1
SLC35C2
SLC35E3
SLC39A2
SLC39A6
STOM
SUSD3
TCF4
TEX11
TMEM139
TMX1
TP53
46 interacting genes:
ADTRP
AGER
AGTRAP
AHNAK
ANXA6
BCL2L2
CACYBP
CALM1
CAPZA1
CEP20
CT45A5
DES
DNAJC30
FBXO7
FBXW5
GFAP
GUCY2D
IMP4
IMPA1
IQGAP1
LNX1
MAL2
MAPT
MDM2
MDM4
NDRG1
NKAPD1
PGM1
RABAC1
S100A1
S100A11
S100A2
S100A4
S100A6
S100A9
S100P
S100Z
SDCBP
SPG21
STK38
SUGT1
TMEM159
TMEM239
TNIP1
TP53
VAV1
Entrez ID
599
6285
HPRD ID
03569
01505
Ensembl ID
ENSG00000129473
ENSG00000160307
Uniprot IDs
Q92843
A0A0S2Z4C5
P04271
PDB IDs
1MK3
1O0L
1ZY3
2Y6W
4CIM
1MQ1
1UWO
2H61
2M49
2PRU
3CZT
3D0Y
3D10
3HCM
4XYN
5CSF
5CSI
5CSJ
5CSN
5D7F
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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