NOVA1 and PCBP1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NOVA1	PCBP1
Description		NOVA alternative splicing regulator 1	poly(rC) binding protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Intracellular Membrane-bounded Organelle Synapse	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing Chemical Synaptic Transmission Locomotory Behavior RNA Splicing Regulation Of Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Cold-induced Thermogenesis	MRNA Splicing, Via Spliceosome Regulation Of Gene Expression RNA Metabolic Process Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process
Pathways			mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28892062) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Cognitive decline rate in late mild cognitive impairment ( 26252872) Eosinophilic esophagitis ( 25407941) Hand grip strength ( 29691431) Metabolite levels ( 23823483) Migraine ( 27182965) Neuritic plaque ( 31497858) Overweight status ( 25133637) Peanut allergy ( 29030101) Plasma anti-thyroid peroxidase levels ( 29678681) Zinc levels ( 26025379)	Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)
Interacting Genes		5 interacting genes: APP PCBP1 RPP14 SMARCC2 SRPK1	49 interacting genes: ANP32A APP CAV3 CELF2 CELF3 DARS1-AS1 ERG EWSR1 FTH1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL HYPK IGF2BP3 KLF1 LMNA MATR3 NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM3 RBM42 RBPMS2 SNCG SNRPA SRPK2 SRSF3 TCERG1 TLE5 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830
Entrez ID		4857	5093
HPRD ID		03693	03128
Ensembl ID		ENSG00000139910	ENSG00000169564
Uniprot IDs		B7Z770 P51513	Q15365 Q53SS8
PDB IDs		1DT4 2ANN 2ANR	1WVN 1ZTG 3VKE
Enriched GO Terms of Interacting Partners?
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