PCBP1 and RBPMS2

Data Source:
BioGRID (two hybrid)

		PCBP1	RBPMS2
Description		poly(rC) binding protein 1	RNA binding protein, mRNA processing factor 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome	Cytoplasm
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding	MRNA Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Gene Expression RNA Metabolic Process Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process	Negative Regulation Of BMP Signaling Pathway Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Smooth Muscle Cell Differentiation
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)	Coronary artery disease ( 29212778) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Platelet count ( 32888494) PR interval ( 32439900)
Interacting Genes		49 interacting genes: ANP32A APP CAV3 CELF2 CELF3 DARS1-AS1 ERG EWSR1 FTH1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL HYPK IGF2BP3 KLF1 LMNA MATR3 NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM3 RBM42 RBPMS2 SNCG SNRPA SRPK2 SRSF3 TCERG1 TLE5 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830	68 interacting genes: AOC1 ARID5A BHLHE40 BOLL C10orf55 C19orf54 CAMK2A CBX2 CELF4 DND1 ESRP1 FAM168A FOXD4L1 FOXD4L3 FOXH1 FUBP3 HNRNPC HNRNPK HNRNPU IFIT2 KLF1 KLHDC7B KRTAP11-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 MAGED1 MKRN3 MSX2 MYPOP PATZ1 PCBP1 PPP1R37 PRR20A PRR20B PRR20C PRR20D PRR20E PTBP2 RALY RBFOX1 RBFOX2 RBM3 RBM41 RBM42 RBM46 RBPMS RHOXF2 SEMA3B SNRPA STRBP TENT5B TEX37 TIAL1 UFSP1 UNC119 USP54 VHL VPS37C ZBTB32 ZC3H10 ZMAT5 ZNF34 ZNF385C
Entrez ID		5093	348093
HPRD ID		03128	18601
Ensembl ID		ENSG00000169564	ENSG00000166831
Uniprot IDs		Q15365 Q53SS8	Q6ZRY4
PDB IDs		1WVN 1ZTG 3VKE	2M9K
Enriched GO Terms of Interacting Partners?
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