PCBP1 and PCBP4

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		PCBP1	PCBP4
Description		poly(rC) binding protein 1	poly(rC) binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome	Nucleus Cytoplasm Cytosol
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding	DNA Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Gene Expression RNA Metabolic Process Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Regulation Of Gene Expression Regulation Of MRNA Stability Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Transcriptional activation of cell cycle inhibitor p21 FOXO-mediated transcription of cell cycle genes
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)
Interacting Genes		49 interacting genes: ANP32A APP CAV3 CELF2 CELF3 DARS1-AS1 ERG EWSR1 FTH1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL HYPK IGF2BP3 KLF1 LMNA MATR3 NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM3 RBM42 RBPMS2 SNCG SNRPA SRPK2 SRSF3 TCERG1 TLE5 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830	5 interacting genes: LYST PCBP1 QKI RBFOX1 RNF138
Entrez ID		5093	57060
HPRD ID		03128	16343
Ensembl ID		ENSG00000169564	ENSG00000090097
Uniprot IDs		Q15365 Q53SS8	A0A024R2Y0 C9J0A4 P57723
PDB IDs		1WVN 1ZTG 3VKE
Enriched GO Terms of Interacting Partners?
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