PCBP1 and MATR3

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		PCBP1	MATR3
Description		poly(rC) binding protein 1	matrin 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome	Nucleus Nuclear Inner Membrane Membrane Nuclear Matrix
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding	RNA Binding Structural Molecule Activity Protein Binding Zinc Ion Binding MiRNA Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Gene Expression RNA Metabolic Process Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process	Activation Of Innate Immune Response Heart Valve Development Ventricular Septum Development Posttranscriptional Regulation Of Gene Expression Innate Immune Response
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases			Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
GWAS		Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)	Body mass index ( 26426971) Malaria ( 31844061) Metabolite levels ( 23823483)
Interacting Genes		49 interacting genes: ANP32A APP CAV3 CELF2 CELF3 DARS1-AS1 ERG EWSR1 FTH1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL HYPK IGF2BP3 KLF1 LMNA MATR3 NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM3 RBM42 RBPMS2 SNCG SNRPA SRPK2 SRSF3 TCERG1 TLE5 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830	99 interacting genes: AIMP2 AKTIP CALM1 CDC42 EGFR ERG GFI1B HNRNPK HTR2B KRT27 KRT34 LMNA MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCBP1 PCBP3 PLEKHG4 PTBP2 PTEN RASD1 SNAP23 SNRNP200 SRPK2 TNFRSF21 TRAF1 TRAF6 TSGA10 TTF2 UBE2I
Entrez ID		5093	9782
HPRD ID		03128	05270
Ensembl ID		ENSG00000169564	ENSG00000015479
Uniprot IDs		Q15365 Q53SS8	A0A0R4J2E8 B3KM87 B4DF66 P43243 Q9H4N1
PDB IDs		1WVN 1ZTG 3VKE
Enriched GO Terms of Interacting Partners?
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