PCBP1 and QKI

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		PCBP1	QKI
Description		poly(rC) binding protein 1	QKI, KH domain containing RNA binding
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome	Nucleus Cytoplasm Synapse
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding	RNA Binding MRNA Binding Protein Binding SH3 Domain Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Gene Expression RNA Metabolic Process Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process	Vasculogenesis MRNA Processing Regulation Of Translation Spermatid Development RNA Splicing Positive Regulation Of Gene Expression Myelination Muscle Cell Differentiation Long-chain Fatty Acid Biosynthetic Process Regulation Of MRNA Splicing, Via Spliceosome MRNA Transport
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)	Diastolic blood pressure ( 27841878) Diisocyanate-induced asthma ( 25918132) Height ( 31562340) Hemoglobin ( 32888494) Incident myocardial infarction ( 26950853) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Platelet distribution width ( 32888494) Red blood cell count ( 29403010) Refractive error ( 32231278) Response to TNF antagonist treatment ( 18615156) Seasonality and depression ( 30217971) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969 30718926)
Interacting Genes		49 interacting genes: ANP32A APP CAV3 CELF2 CELF3 DARS1-AS1 ERG EWSR1 FTH1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL HYPK IGF2BP3 KLF1 LMNA MATR3 NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM3 RBM42 RBPMS2 SNCG SNRPA SRPK2 SRSF3 TCERG1 TLE5 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830	50 interacting genes: APP ATXN1 CARM1 CCND3 CDKN2D DAZ1 DAZ4 DEPP1 DMRTB1 FBXO7 FHL3 FUBP3 HCLS1 HNRNPH2 HNRNPK IL7R LSM3 MIR141 MIR19B2 MIR200A MIR34B MIR34C MIR7-1 NABP1 PCBP1 PCBP2 PCBP4 PIAS1 PRKAB2 PRMT1 PSMF1 PTBP1 PTBP2 RALY RBFOX1 RBFOX2 RBM11 RBM14 RBM23 RBPMS RNF138 SERF2 SNRPA TEX11 THAP1 TIAL1 TSG101 U2AF2 USH1C WDR77
Entrez ID		5093	9444
HPRD ID		03128	06691
Ensembl ID		ENSG00000169564	ENSG00000112531
Uniprot IDs		Q15365 Q53SS8	Q8WY44 Q96PU8
PDB IDs		1WVN 1ZTG 3VKE	4JVH
Enriched GO Terms of Interacting Partners?
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