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CCN3 and CCN2
Data Source:
HPRD
(in vitro, two hybrid)
CCN3
CCN2
Description
cellular communication network factor 3
cellular communication network factor 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Cytoplasm
Gap Junction
Axon
Dendrite
Extracellular Matrix
Neuronal Cell Body
Intracellular Membrane-bounded Organelle
Collagen-containing Extracellular Matrix
Extracellular Region
Extracellular Space
Cis-Golgi Network
Cytosol
Plasma Membrane
Cell Cortex
Extracellular Matrix
Perinuclear Region Of Cytoplasm
Collagen-containing Extracellular Matrix
Molecular Function
Notch Binding
Integrin Binding
Protein Binding
Insulin-like Growth Factor Binding
Growth Factor Activity
Heparin Binding
Fibronectin Binding
Integrin Binding
Protein Binding
Insulin-like Growth Factor Binding
Protein C-terminus Binding
Growth Factor Activity
Heparin Binding
Biological Process
Angiogenesis
Chondrocyte Differentiation
Cell Adhesion
Signal Transduction
Regulation Of Gene Expression
Fibroblast Migration
Negative Regulation Of Myotube Differentiation
Smooth Muscle Cell Migration
Negative Regulation Of Cell Growth
Cell Adhesion Mediated By Integrin
Endothelial Cell Chemotaxis
Type B Pancreatic Cell Proliferation
Positive Regulation Of Notch Signaling Pathway
Negative Regulation Of Insulin Secretion
Smooth Muscle Cell Proliferation
Negative Regulation Of Inflammatory Response
Cell Chemotaxis
Negative Regulation Of SMAD Protein Signal Transduction
Negative Regulation Of Cell Death
Hematopoietic Stem Cell Homeostasis
Endothelial Cell-cell Adhesion
Negative Regulation Of Monocyte Chemotaxis
Negative Regulation Of NIK/NF-kappaB Signaling
Negative Regulation Of Chondrocyte Proliferation
Negative Regulation Of Sensory Perception Of Pain
Bone Regeneration
Cartilage Condensation
Ossification
Angiogenesis
Tissue Homeostasis
Positive Regulation Of Protein Phosphorylation
Transcription Initiation From RNA Polymerase II Promoter
Cell Adhesion
Cell-matrix Adhesion
Signal Transduction
Integrin-mediated Signaling Pathway
Aging
Positive Regulation Of Cell Population Proliferation
Fibroblast Growth Factor Receptor Signaling Pathway
Epidermis Development
Response To Wounding
Response To Glucose
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cell Death
Cell Migration
Cell Differentiation
Lung Development
Regulation Of Chondrocyte Differentiation
Response To Estradiol
Positive Regulation Of Collagen Biosynthetic Process
Response To Anoxia
Intracellular Signal Transduction
Chondrocyte Proliferation
Response To Amino Acid
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Peptide Hormone
Positive Regulation Of Cell Differentiation
Positive Regulation Of JNK Cascade
Positive Regulation Of Cell Activation
Response To Mineralocorticoid
Positive Regulation Of Stress Fiber Assembly
Cytosolic Calcium Ion Transport
Positive Regulation Of Cardiac Muscle Contraction
Negative Regulation Of Cell Death
Extracellular Matrix Constituent Secretion
Positive Regulation Of G0 To G1 Transition
Positive Regulation Of ERK1 And ERK2 Cascade
Response To Fatty Acid
DNA Biosynthetic Process
Reactive Oxygen Species Metabolic Process
Pathways
YAP1- and WWTR1 (TAZ)-stimulated gene expression
RUNX3 regulates YAP1-mediated transcription
Drugs
Insulin pork
Diseases
GWAS
Interacting Genes
29 interacting genes:
ADSL
ANKRD11
APOL6
C11orf87
CCN2
CDKN1A
COL8A1
DLL1
FAM90A1
FBLN1
FN1
FRS3
GJA1
HOXA1
IGF1
IGF2
INS
ITGAV
KRTAP5-6
LCE1A
LCE3D
NID2
NOTCH1
POLR2L
POU4F2
RECK
S100A4
TNIP3
ZNF330
13 interacting genes:
ACTB
AP3D1
CCN3
ERBB4
FBLN1
HSPG2
LIMS1
LRP1
MTDH
TGFB1
TGFB2
TGFB3
VEGFA
Entrez ID
4856
1490
HPRD ID
01291
00412
Ensembl ID
ENSG00000136999
ENSG00000118523
Uniprot IDs
A0A024R9J4
P48745
P29279
Q5M8T4
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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