CCN3 and C11orf87

Data Source:
BioGRID (two hybrid)

		CCN3	C11orf87
Description		cellular communication network factor 3	chromosome 11 open reading frame 87
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Gap Junction Axon Dendrite Extracellular Matrix Neuronal Cell Body Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix	Integral Component Of Membrane
	Molecular Function	Notch Binding Integrin Binding Protein Binding Insulin-like Growth Factor Binding Growth Factor Activity Heparin Binding	Protein Binding
	Biological Process	Angiogenesis Chondrocyte Differentiation Cell Adhesion Signal Transduction Regulation Of Gene Expression Fibroblast Migration Negative Regulation Of Myotube Differentiation Smooth Muscle Cell Migration Negative Regulation Of Cell Growth Cell Adhesion Mediated By Integrin Endothelial Cell Chemotaxis Type B Pancreatic Cell Proliferation Positive Regulation Of Notch Signaling Pathway Negative Regulation Of Insulin Secretion Smooth Muscle Cell Proliferation Negative Regulation Of Inflammatory Response Cell Chemotaxis Negative Regulation Of SMAD Protein Signal Transduction Negative Regulation Of Cell Death Hematopoietic Stem Cell Homeostasis Endothelial Cell-cell Adhesion Negative Regulation Of Monocyte Chemotaxis Negative Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of Chondrocyte Proliferation Negative Regulation Of Sensory Perception Of Pain Bone Regeneration
Pathways
Drugs		Insulin pork
Diseases
GWAS			Knee osteoarthritis ( 28916551) Schizophrenia ( 28991256 25056061 29483656 30285260) Systolic blood pressure ( 27841878)
Interacting Genes		29 interacting genes: ADSL ANKRD11 APOL6 C11orf87 CCN2 CDKN1A COL8A1 DLL1 FAM90A1 FBLN1 FN1 FRS3 GJA1 HOXA1 IGF1 IGF2 INS ITGAV KRTAP5-6 LCE1A LCE3D NID2 NOTCH1 POLR2L POU4F2 RECK S100A4 TNIP3 ZNF330	22 interacting genes: CCN3 CYSRT1 KRT34 KRT40 KRT83 KRTAP1-1 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP19-1 KRTAP2-3 KRTAP2-4 KRTAP5-9 KRTAP6-3 NOTCH2NLA RBPMS SLC15A2 SRPK1 TNS2 TRIP6 WWOX
Entrez ID		4856	399947
HPRD ID		01291	14218
Ensembl ID		ENSG00000136999	ENSG00000185742
Uniprot IDs		A0A024R9J4 P48745	A0A158RFU1 Q6NUJ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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