Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
CCN2 and TGFB3
Data Source:
HPRD
(in vivo)
CCN2
TGFB3
Description
cellular communication network factor 2
transforming growth factor beta 3
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cis-Golgi Network
Cytosol
Plasma Membrane
Cell Cortex
Extracellular Matrix
Perinuclear Region Of Cytoplasm
Collagen-containing Extracellular Matrix
Extracellular Region
Extracellular Space
Nucleus
Plasma Membrane
Cell Surface
T-tubule
Platelet Alpha Granule Lumen
Neuronal Cell Body
Intracellular Membrane-bounded Organelle
Collagen-containing Extracellular Matrix
Molecular Function
Fibronectin Binding
Integrin Binding
Protein Binding
Insulin-like Growth Factor Binding
Protein C-terminus Binding
Growth Factor Activity
Heparin Binding
Type II Transforming Growth Factor Beta Receptor Binding
Cytokine Activity
Protein Binding
Growth Factor Activity
Type I Transforming Growth Factor Beta Receptor Binding
Type III Transforming Growth Factor Beta Receptor Binding
Identical Protein Binding
Protein-containing Complex Binding
Transforming Growth Factor Beta Binding
Biological Process
Cartilage Condensation
Ossification
Angiogenesis
Tissue Homeostasis
Positive Regulation Of Protein Phosphorylation
Transcription Initiation From RNA Polymerase II Promoter
Cell Adhesion
Cell-matrix Adhesion
Signal Transduction
Integrin-mediated Signaling Pathway
Aging
Positive Regulation Of Cell Population Proliferation
Fibroblast Growth Factor Receptor Signaling Pathway
Epidermis Development
Response To Wounding
Response To Glucose
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cell Death
Cell Migration
Cell Differentiation
Lung Development
Regulation Of Chondrocyte Differentiation
Response To Estradiol
Positive Regulation Of Collagen Biosynthetic Process
Response To Anoxia
Intracellular Signal Transduction
Chondrocyte Proliferation
Response To Amino Acid
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Peptide Hormone
Positive Regulation Of Cell Differentiation
Positive Regulation Of JNK Cascade
Positive Regulation Of Cell Activation
Response To Mineralocorticoid
Positive Regulation Of Stress Fiber Assembly
Cytosolic Calcium Ion Transport
Positive Regulation Of Cardiac Muscle Contraction
Negative Regulation Of Cell Death
Extracellular Matrix Constituent Secretion
Positive Regulation Of G0 To G1 Transition
Positive Regulation Of ERK1 And ERK2 Cascade
Response To Fatty Acid
DNA Biosynthetic Process
Reactive Oxygen Species Metabolic Process
Activation Of MAPK Activity
Response To Hypoxia
In Utero Embryonic Development
Platelet Degranulation
Transforming Growth Factor Beta Receptor Signaling Pathway
Salivary Gland Morphogenesis
Female Pregnancy
Aging
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Macrophage Cytokine Production
Positive Regulation Of Bone Mineralization
BMP Signaling Pathway
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Mammary Gland Development
Response To Progesterone
Positive Regulation Of Collagen Biosynthetic Process
Response To Laminar Fluid Shear Stress
Wound Healing
Regulation Of Cell Population Proliferation
Odontogenesis
Uterine Wall Breakdown
Positive Regulation Of Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Response To Estrogen
Ossification Involved In Bone Remodeling
Cell-cell Junction Organization
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Lung Alveolus Development
Digestive Tract Development
Embryonic Neurocranium Morphogenesis
Inner Ear Development
Positive Regulation Of Protein Secretion
Positive Regulation Of Filopodium Assembly
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Cell Division
Face Morphogenesis
Frontal Suture Morphogenesis
Positive Regulation Of SMAD Protein Signal Transduction
SMAD Protein Signal Transduction
Secondary Palate Development
Detection Of Hypoxia
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Positive Regulation Of Tight Junction Disassembly
Pathways
YAP1- and WWTR1 (TAZ)-stimulated gene expression
RUNX3 regulates YAP1-mediated transcription
Platelet degranulation
Molecules associated with elastic fibres
ECM proteoglycans
Drugs
1,4-Dioxane
Diseases
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Graft-versus-host disease
Ossification of the posterior longitudinal ligament of spine (OPLL)
Allograft rejection
Isolated orofacial clefts, including: Cleft lip with or without cleft palate; Cleft palate
GWAS
Interacting Genes
13 interacting genes:
ACTB
AP3D1
CCN3
ERBB4
FBLN1
HSPG2
LIMS1
LRP1
MTDH
TGFB1
TGFB2
TGFB3
VEGFA
13 interacting genes:
ACVRL1
CCL20
CCN2
CHMP2A
ENG
FMOD
LTBP3
SDC4
TGFB2
TGFBR1
TGFBR2
TGFBR3
VASN
Entrez ID
1490
7043
HPRD ID
00412
01829
Ensembl ID
ENSG00000118523
ENSG00000119699
Uniprot IDs
P29279
Q5M8T4
A5YM40
B3KVH9
P10600
PDB IDs
1KTZ
1TGJ
1TGK
2PJY
3EO1
4UM9
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?