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CCN2 and LIMS1
Data Source:
BioGRID
(two hybrid)
CCN2
LIMS1
Description
cellular communication network factor 2
LIM zinc finger domain containing 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cis-Golgi Network
Cytosol
Plasma Membrane
Cell Cortex
Extracellular Matrix
Perinuclear Region Of Cytoplasm
Collagen-containing Extracellular Matrix
Cytoplasm
Cytosol
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Protein-containing Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Fibronectin Binding
Integrin Binding
Protein Binding
Insulin-like Growth Factor Binding
Protein C-terminus Binding
Growth Factor Activity
Heparin Binding
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Protein-containing Complex Binding
Biological Process
Cartilage Condensation
Ossification
Angiogenesis
Tissue Homeostasis
Positive Regulation Of Protein Phosphorylation
Transcription Initiation From RNA Polymerase II Promoter
Cell Adhesion
Cell-matrix Adhesion
Signal Transduction
Integrin-mediated Signaling Pathway
Aging
Positive Regulation Of Cell Population Proliferation
Fibroblast Growth Factor Receptor Signaling Pathway
Epidermis Development
Response To Wounding
Response To Glucose
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cell Death
Cell Migration
Cell Differentiation
Lung Development
Regulation Of Chondrocyte Differentiation
Response To Estradiol
Positive Regulation Of Collagen Biosynthetic Process
Response To Anoxia
Intracellular Signal Transduction
Chondrocyte Proliferation
Response To Amino Acid
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Peptide Hormone
Positive Regulation Of Cell Differentiation
Positive Regulation Of JNK Cascade
Positive Regulation Of Cell Activation
Response To Mineralocorticoid
Positive Regulation Of Stress Fiber Assembly
Cytosolic Calcium Ion Transport
Positive Regulation Of Cardiac Muscle Contraction
Negative Regulation Of Cell Death
Extracellular Matrix Constituent Secretion
Positive Regulation Of G0 To G1 Transition
Positive Regulation Of ERK1 And ERK2 Cascade
Response To Fatty Acid
DNA Biosynthetic Process
Reactive Oxygen Species Metabolic Process
Epithelial To Mesenchymal Transition
Cell Aging
Positive Regulation Of Gene Expression
Positive Regulation Of Cell-substrate Adhesion
Tumor Necrosis Factor-mediated Signaling Pathway
Cell Junction Assembly
Positive Regulation Of GTPase Activity
Establishment Of Protein Localization
Cell-cell Junction Organization
Negative Regulation Of Transcription, DNA-templated
Regulation Of Epithelial Cell Proliferation
Positive Regulation Of Focal Adhesion Assembly
Cellular Response To Transforming Growth Factor Beta Stimulus
Cell-cell Adhesion
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways
YAP1- and WWTR1 (TAZ)-stimulated gene expression
RUNX3 regulates YAP1-mediated transcription
Cell-extracellular matrix interactions
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Diseases
GWAS
Apolipoprotein B levels (
32203549
)
Beard thickness (
26926045
)
Birth weight (
31043758
)
Excessive hairiness (
29895819
)
Eyebrow thickness (
26926045
)
Immature fraction of reticulocytes (
32888494
)
LDL cholesterol (
30275531
)
LDL cholesterol levels (
32203549
)
Monobrow thickness (
26926045
)
Scalp hair shape (
26926045
)
Interacting Genes
13 interacting genes:
ACTB
AP3D1
CCN3
ERBB4
FBLN1
HSPG2
LIMS1
LRP1
MTDH
TGFB1
TGFB2
TGFB3
VEGFA
47 interacting genes:
ADAMTS9
ATXN10
CATSPER1
CCN2
COL8A1
CSRP3
CWF19L2
DAPK1
EHMT2
FAM90A1
FERMT2
FERMT3
FMR1
GEM
ILK
INO80B
IPO7
KPRP
LMO3
LPXN
MBIP
MYO15B
NCK2
NEB
OSR2
PARVA
PEG3
PLCE1
RAD51D
RBBP8
RSU1
SCNM1
SMURF1
TBC1D22B
TCEA2
TGFBR1
TMSB4X
TRIO
TTN
USP11
ZIM2
ZMYM4
ZNF160
ZNF410
ZNF417
ZNF564
ZNF587
Entrez ID
1490
3987
HPRD ID
00412
03978
Ensembl ID
ENSG00000118523
ENSG00000169756
Uniprot IDs
P29279
Q5M8T4
P48059
PDB IDs
1G47
1NYP
1U5S
2COR
2D8X
2KBX
3F6Q
4HI8
4HI9
6MIF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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