PGRMC1 and CIAO1

Data Source:
BioGRID (two hybrid)

		PGRMC1	CIAO1
Description		progesterone receptor membrane component 1	cytosolic iron-sulfur assembly component 1
Image
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse	Cytoplasm MMXD Complex CIA Complex
	Molecular Function	Amyloid-beta Binding Steroid Binding Protein Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding	Protein Binding
	Biological Process	Heme Biosynthetic Process Neutrophil Degranulation	Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Positive Regulation Of Cell Population Proliferation Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer
Pathways		Neutrophil degranulation	Cytosolic iron-sulfur cluster assembly
Drugs		Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS
Interacting Genes		20 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 MTNR1A PAM16 PGRMC2 SCAP SGTB TMEM213 ZNF71	18 interacting genes: APP CCDC7 CIAO2A CIAO2B GOLM1 HAUS3 MEOX1 MEOX2 PGRMC1 RGS2 SF1 SHISA6 SLC4A7 SRPK1 TCP10L TOP3B URI1 WT1
Entrez ID		10857	9391
HPRD ID		02338	16057
Ensembl ID		ENSG00000101856	ENSG00000144021
Uniprot IDs		O00264 Q6IB11	O76071
PDB IDs		4X8Y	3FM0
Enriched GO Terms of Interacting Partners?
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