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MNAT1 and EEF1A1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
MNAT1
EEF1A1
Description
MNAT1 component of CDK activating kinase
eukaryotic translation elongation factor 1 alpha 1
Image
GO Annotations
Cellular Component
Transcription Factor TFIIH Core Complex
Nucleoplasm
Transcription Factor TFIIH Holo Complex
Cyclin-dependent Protein Kinase Activating Kinase Holoenzyme Complex
CAK-ERCC2 Complex
Transcription Factor TFIIK Complex
Extracellular Region
Extracellular Space
Nucleus
Nucleolus
Cytoplasm
Cytosol
Eukaryotic Translation Elongation Factor 1 Complex
Plasma Membrane
Membrane
Cortical Actin Cytoskeleton
Ruffle Membrane
Secretory Granule Lumen
Extracellular Exosome
Cytoplasmic Side Of Lysosomal Membrane
Ficolin-1-rich Granule Lumen
Molecular Function
Protein Binding
Zinc Ion Binding
Protein N-terminus Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
TRNA Binding
RNA Binding
Translation Elongation Factor Activity
GTPase Activity
Protein Binding
Calmodulin Binding
GTP Binding
Kinase Binding
Protein Kinase Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair, Preincision Complex Assembly
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Adult Heart Development
Ventricular System Development
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Smooth Muscle Cell Proliferation
Response To Calcium Ion
Protein-containing Complex Assembly
Negative Regulation Of DNA Helicase Activity
Translation
Translational Elongation
Neutrophil Degranulation
Cellular Response To Epidermal Growth Factor Stimulus
Regulation Of D-erythro-sphingosine Kinase Activity
Regulation Of Chaperone-mediated Autophagy
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Tat-mediated elongation of the HIV-1 transcript
NoRC negatively regulates rRNA expression
Formation of Incision Complex in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
Cyclin E associated events during G1/S transition
Cyclin D associated events in G1
Cyclin A/B1/B2 associated events during G2/M transition
Cyclin A:Cdk2-associated events at S phase entry
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Eukaryotic Translation Elongation
Eukaryotic Translation Elongation
Peptide chain elongation
HSF1 activation
Neutrophil degranulation
Protein methylation
Chaperone Mediated Autophagy
Drugs
Zinc
Guanosine-5'-Diphosphate
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease (
29631575
)
Gut microbiota (bacterial taxa, rank normal transformation method) (
32572223
)
Immune reponse to smallpox (secreted IFN-alpha) (
22610502
)
Refractive error (
32231278
)
Interacting Genes
48 interacting genes:
BEX3
BRCA1
CDK7
COPS6
DMAP1
E2F1
EEF1A1
ERCC2
ERCC3
ESR1
FOXP1
GOLGA2
GTF2E2
GTF2H1
GTF2H2
HPS6
LRIF1
MAGEC2
MAGEE2
MCM7
MDM4
MKRN3
MTA1
NKX3-1
POLR2A
POU2F1
POU2F2
POU5F1
RB1
RBM48
RNF32
RNF41
RNF7
SUPT5H
TET2
TP53
TRIM14
TRIM17
TRIM2
TRIM21
TRIM26
TRIM31
TRIM34
TRIM39
TRIM5
TRIM9
TRIML1
USP2
130 interacting genes:
ABTB2
ACTB
ALPL
ANKRD24
ANXA7
APLP1
AQP2
ARIH2
AXIN1
BBS1
BBS2
BBS4
BRMS1
BTBD2
CASP2
CCDC130
CCL18
CDC25A
CDKN1A
CKS2
COX17
CRADD
CRCT1
CSRP2
DARS1
DIABLO
DLEU1
DUSP7
DYNLL1
DYSF
EIF3F
EP300
EXOSC4
FAS
GADD45A
GADD45G
HSPB2
HSPE1
HTRA2
IKBKG
IMMT
ITGB1BP1
ITSN1
KCNE3
KIF1B
LAMA4
LAMTOR1
LAMTOR5
LSM3
MAD2L1BP
MAGED2
MAP3K14
MAPK14
MLLT3
MNAT1
MRM1
MRPL42
MTRNR2L1
MYOC
NEU1
NRAS
NREP
ORMDL3
PABPC4
PAEP
PAFAH1B3
PAPSS1
PCDHA4
PFN2
PHYHIP
PKN2
PLAUR
PLCG1
POLE2
POLR2C
PQBP1
PRKCD
PSG9
PSMD11
PTPN4
PTPRCAP
PTPRF
RAB27A
RAP2A
RBBP8
RFC5
RGS12
RND1
RNF10
RPA2
RPLP1
RRAS
RSRC1
SARS2
SDHAF2
SERPINB5
SERPINB9
SFN
SHBG
SMAD2
SMAD4
SMN1
SNCA
SPP1
SSR1
STAT6
STMN2
SULT1E1
SUMO2
TAF9
TGIF1
TK1
TMPRSS3
TNFSF11
TP53BP2
TPT1
TRDMT1
TSPY1
TSPYL2
TTLL12
TTR
UBQLN4
WARS1
XPO5
XRN2
YWHAG
ZBTB16
ZCCHC10
ZNF24
ZPR1
Entrez ID
4331
1915
HPRD ID
04042
00559
Ensembl ID
ENSG00000020426
ENSG00000156508
Uniprot IDs
A0A024R669
A0A024R688
P51948
P68104
Q6IPS9
PDB IDs
1G25
6NMI
6O9L
6O9M
6XBZ
6XD3
1SYW
3C5J
6ZMO
Enriched GO Terms of Interacting Partners
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