EEF1A1 and TRDMT1

Data Source:
HPRD (two hybrid)

		EEF1A1	TRDMT1
Description		eukaryotic translation elongation factor 1 alpha 1	tRNA aspartic acid methyltransferase 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Eukaryotic Translation Elongation Factor 1 Complex Plasma Membrane Membrane Cortical Actin Cytoskeleton Ruffle Membrane Secretory Granule Lumen Extracellular Exosome Cytoplasmic Side Of Lysosomal Membrane Ficolin-1-rich Granule Lumen	Nucleoplasm Cytoplasm
	Molecular Function	TRNA Binding RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding Calmodulin Binding GTP Binding Kinase Binding Protein Kinase Binding	RNA Binding TRNA Methyltransferase Activity TRNA (cytosine-5-)-methyltransferase Activity
	Biological Process	Translation Translational Elongation Neutrophil Degranulation Cellular Response To Epidermal Growth Factor Stimulus Regulation Of D-erythro-sphingosine Kinase Activity Regulation Of Chaperone-mediated Autophagy	Response To Amphetamine TRNA Modification TRNA Methylation TRNA Stabilization
Pathways		Eukaryotic Translation Elongation Eukaryotic Translation Elongation Peptide chain elongation HSF1 activation Neutrophil degranulation Protein methylation Chaperone Mediated Autophagy	tRNA modification in the nucleus and cytosol
Drugs		Zinc Guanosine-5'-Diphosphate Copper Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Pentamidine S-adenosyl-L-homocysteine Glycerin
Diseases
GWAS			Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Telomere length ( 24478790)
Interacting Genes		130 interacting genes: ABTB2 ACTB ALPL ANKRD24 ANXA7 APLP1 AQP2 ARIH2 AXIN1 BBS1 BBS2 BBS4 BRMS1 BTBD2 CASP2 CCDC130 CCL18 CDC25A CDKN1A CKS2 COX17 CRADD CRCT1 CSRP2 DARS1 DIABLO DLEU1 DUSP7 DYNLL1 DYSF EIF3F EP300 EXOSC4 FAS GADD45A GADD45G HSPB2 HSPE1 HTRA2 IKBKG IMMT ITGB1BP1 ITSN1 KCNE3 KIF1B LAMA4 LAMTOR1 LAMTOR5 LSM3 MAD2L1BP MAGED2 MAP3K14 MAPK14 MLLT3 MNAT1 MRM1 MRPL42 MTRNR2L1 MYOC NEU1 NRAS NREP ORMDL3 PABPC4 PAEP PAFAH1B3 PAPSS1 PCDHA4 PFN2 PHYHIP PKN2 PLAUR PLCG1 POLE2 POLR2C PQBP1 PRKCD PSG9 PSMD11 PTPN4 PTPRCAP PTPRF RAB27A RAP2A RBBP8 RFC5 RGS12 RND1 RNF10 RPA2 RPLP1 RRAS RSRC1 SARS2 SDHAF2 SERPINB5 SERPINB9 SFN SHBG SMAD2 SMAD4 SMN1 SNCA SPP1 SSR1 STAT6 STMN2 SULT1E1 SUMO2 TAF9 TGIF1 TK1 TMPRSS3 TNFSF11 TP53BP2 TPT1 TRDMT1 TSPY1 TSPYL2 TTLL12 TTR UBQLN4 WARS1 XPO5 XRN2 YWHAG ZBTB16 ZCCHC10 ZNF24 ZPR1	14 interacting genes: APP COPS6 DDX24 EEF1A1 GBE1 LRIF1 NFRKB RBM48 SETDB1 SNRPD3 STX1A TBC1D2B UNC119 UTP14A
Entrez ID		1915	1787
HPRD ID		00559	16001
Ensembl ID		ENSG00000156508	ENSG00000107614
Uniprot IDs		P68104 Q6IPS9	A0A0U1U562 B4DQZ2 O14717 Q6ICS7 Q7Z3E4
PDB IDs		1SYW 3C5J 6ZMO	1G55
Enriched GO Terms of Interacting Partners?
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