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MNAT1 and MTA1
Data Source:
HPRD
(two hybrid, in vitro, in vivo)
MNAT1
MTA1
Description
MNAT1 component of CDK activating kinase
metastasis associated 1
Image
GO Annotations
Cellular Component
Transcription Factor TFIIH Core Complex
Nucleoplasm
Transcription Factor TFIIH Holo Complex
Cyclin-dependent Protein Kinase Activating Kinase Holoenzyme Complex
CAK-ERCC2 Complex
Transcription Factor TFIIK Complex
Nucleus
Nuclear Envelope
Nucleoplasm
Cytoplasm
Cytosol
Microtubule
NuRD Complex
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Binding
Zinc Ion Binding
Protein N-terminus Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Repressing Transcription Factor Binding
Chromatin Binding
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Binding
Zinc Ion Binding
Histone Deacetylase Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair, Preincision Complex Assembly
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Adult Heart Development
Ventricular System Development
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Smooth Muscle Cell Proliferation
Response To Calcium Ion
Protein-containing Complex Assembly
Negative Regulation Of DNA Helicase Activity
Negative Regulation Of Transcription By RNA Polymerase II
Double-strand Break Repair
Signal Transduction
Response To Ionizing Radiation
Histone Deacetylation
Circadian Regulation Of Gene Expression
Regulation Of Gene Expression, Epigenetic
Entrainment Of Circadian Clock By Photoperiod
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Locomotor Rhythm
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Protein Autoubiquitination
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Tat-mediated elongation of the HIV-1 transcript
NoRC negatively regulates rRNA expression
Formation of Incision Complex in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
Cyclin E associated events during G1/S transition
Cyclin D associated events in G1
Cyclin A/B1/B2 associated events during G2/M transition
Cyclin A:Cdk2-associated events at S phase entry
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
RUNX1 regulates transcription of genes involved in differentiation of HSCs
HDACs deacetylate histones
SUMOylation of transcription factors
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease (
29631575
)
Gut microbiota (bacterial taxa, rank normal transformation method) (
32572223
)
Immune reponse to smallpox (secreted IFN-alpha) (
22610502
)
Refractive error (
32231278
)
Heel bone mineral density (
30598549
)
Interacting Genes
48 interacting genes:
BEX3
BRCA1
CDK7
COPS6
DMAP1
E2F1
EEF1A1
ERCC2
ERCC3
ESR1
FOXP1
GOLGA2
GTF2E2
GTF2H1
GTF2H2
HPS6
LRIF1
MAGEC2
MAGEE2
MCM7
MDM4
MKRN3
MTA1
NKX3-1
POLR2A
POU2F1
POU2F2
POU5F1
RB1
RBM48
RNF32
RNF41
RNF7
SUPT5H
TET2
TP53
TRIM14
TRIM17
TRIM2
TRIM21
TRIM26
TRIM31
TRIM34
TRIM39
TRIM5
TRIM9
TRIML1
USP2
45 interacting genes:
BCL11A
BLOC1S1
CCNH
CSNK1G2
CYSRT1
DDX18
DYNLL1
E2F1
ERCC6
ESR1
FHL3
GPR183
GRB2
H3-4
HDAC1
HDAC2
HIF1A
ITGB3BP
JUN
KHDRBS2
KPNA4
KRT31
KRT40
KRTAP10-8
LMO4
LRRK2
LZTS2
MAGEA11
MBD3L2
MNAT1
NACC2
NBPF19
NELFCD
NOTCH2NLA
PICK1
PLEKHG4
RBBP4
SAT1
SH3GL1
SH3GLB1
SUMO2
TEX11
TP53
TRIM25
UBE2I
Entrez ID
4331
9112
HPRD ID
04042
04633
Ensembl ID
ENSG00000020426
ENSG00000182979
Uniprot IDs
A0A024R669
A0A024R688
P51948
Q13330
Q9BRL8
PDB IDs
1G25
6NMI
6O9L
6O9M
6XBZ
6XD3
4BKX
4PBY
4PBZ
4PC0
5FXY
5ICN
6G16
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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