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EEF1A1 and PQBP1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
EEF1A1
PQBP1
Description
eukaryotic translation elongation factor 1 alpha 1
polyglutamine binding protein 1
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Nucleolus
Cytoplasm
Cytosol
Eukaryotic Translation Elongation Factor 1 Complex
Plasma Membrane
Membrane
Cortical Actin Cytoskeleton
Ruffle Membrane
Secretory Granule Lumen
Extracellular Exosome
Cytoplasmic Side Of Lysosomal Membrane
Ficolin-1-rich Granule Lumen
Nucleus
Nucleoplasm
Cytoplasm
Cytoplasmic Stress Granule
Nuclear Body
Nuclear Speck
Neuronal Ribonucleoprotein Granule
Molecular Function
TRNA Binding
RNA Binding
Translation Elongation Factor Activity
GTPase Activity
Protein Binding
Calmodulin Binding
GTP Binding
Kinase Binding
Protein Kinase Binding
DNA Binding
Double-stranded DNA Binding
Transcription Coactivator Activity
Protein Binding
Ribonucleoprotein Complex Binding
Biological Process
Translation
Translational Elongation
Neutrophil Degranulation
Cellular Response To Epidermal Growth Factor Stimulus
Regulation Of D-erythro-sphingosine Kinase Activity
Regulation Of Chaperone-mediated Autophagy
Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
Activation Of Innate Immune Response
Positive Regulation Of Defense Response To Virus By Host
Regulation Of Transcription, DNA-templated
Neuron Projection Development
Positive Regulation Of Type I Interferon Production
Regulation Of RNA Splicing
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Regulation Of Dendrite Morphogenesis
Defense Response To Virus
Cellular Response To Exogenous DsRNA
Pathways
Eukaryotic Translation Elongation
Eukaryotic Translation Elongation
Peptide chain elongation
HSF1 activation
Neutrophil degranulation
Protein methylation
Chaperone Mediated Autophagy
mRNA Splicing - Major Pathway
Drugs
Zinc
Guanosine-5'-Diphosphate
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
Non-syndromic X-linked mental retardation
GWAS
Interacting Genes
130 interacting genes:
ABTB2
ACTB
ALPL
ANKRD24
ANXA7
APLP1
AQP2
ARIH2
AXIN1
BBS1
BBS2
BBS4
BRMS1
BTBD2
CASP2
CCDC130
CCL18
CDC25A
CDKN1A
CKS2
COX17
CRADD
CRCT1
CSRP2
DARS1
DIABLO
DLEU1
DUSP7
DYNLL1
DYSF
EIF3F
EP300
EXOSC4
FAS
GADD45A
GADD45G
HSPB2
HSPE1
HTRA2
IKBKG
IMMT
ITGB1BP1
ITSN1
KCNE3
KIF1B
LAMA4
LAMTOR1
LAMTOR5
LSM3
MAD2L1BP
MAGED2
MAP3K14
MAPK14
MLLT3
MNAT1
MRM1
MRPL42
MTRNR2L1
MYOC
NEU1
NRAS
NREP
ORMDL3
PABPC4
PAEP
PAFAH1B3
PAPSS1
PCDHA4
PFN2
PHYHIP
PKN2
PLAUR
PLCG1
POLE2
POLR2C
PQBP1
PRKCD
PSG9
PSMD11
PTPN4
PTPRCAP
PTPRF
RAB27A
RAP2A
RBBP8
RFC5
RGS12
RND1
RNF10
RPA2
RPLP1
RRAS
RSRC1
SARS2
SDHAF2
SERPINB5
SERPINB9
SFN
SHBG
SMAD2
SMAD4
SMN1
SNCA
SPP1
SSR1
STAT6
STMN2
SULT1E1
SUMO2
TAF9
TGIF1
TK1
TMPRSS3
TNFSF11
TP53BP2
TPT1
TRDMT1
TSPY1
TSPYL2
TTLL12
TTR
UBQLN4
WARS1
XPO5
XRN2
YWHAG
ZBTB16
ZCCHC10
ZNF24
ZPR1
24 interacting genes:
APBB1
APP
AQR
ATXN1
CLTB
EEF1A1
ERG28
ESR1
GOLGA2
HNRNPH2
LNX1
LRIF1
LZTS2
MAPRE1
MED31
POLR2A
POU3F2
RAB8A
RCVRN
SFTPC
TLX3
TXNL4A
WBP11
WDR77
Entrez ID
1915
10084
HPRD ID
00559
02354
Ensembl ID
ENSG00000156508
ENSG00000102103
Uniprot IDs
P68104
Q6IPS9
A0A0S2Z4V5
O60828
PDB IDs
1SYW
3C5J
6ZMO
4BWQ
4BWS
4CDO
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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