MEIS2 and NDUFB7

Data Source:
BioGRID (two hybrid)

		MEIS2	NDUFB7
Description		Meis homeobox 2	NADH:ubiquinone oxidoreductase subunit B7
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GO Annotations	Cellular Component	Chromatin Nucleus Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Intermembrane Space
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Visual Learning Response To Mechanical Stimulus Embryonic Pattern Specification Animal Organ Morphogenesis Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly
Pathways			Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Postprandial triglyceride response ( 32603185) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)
Interacting Genes		49 interacting genes: ADRA2C ANTKMT ANXA1 APP ARNT2 BPIFA1 C1orf94 C9orf24 CARTPT CCDC196 CTAG1A CTAG1B DGCR6 FAM136A FAM168A HOXA13 HOXA9 IGFBP6 ITGB3BP KRTAP10-8 KRTAP11-1 KRTAP13-1 KRTAP19-2 KRTAP19-6 KRTAP22-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 MCCD1 NDUFB7 NOTO NUP58 OIP5 OSGIN1 PBX1 PBX4 POU2AF1 POU6F2 PTK6 RBPMS RUSC1 SCT SQSTM1 TBX2 TIMM10B TRIM25 TRIM42 VGLL1 ZNHIT3	41 interacting genes: AGBL2 ANKRD36B ATG9A C1orf109 CAPN1 CCDC24 CCNC CDCA7L CDKN2D CHIC2 CINP CKAP4 CTNNA3 ENKD1 FAM161B FAM90A1 GEM GPATCH2L GYS1 KRTAP10-10 LMO2 MAGOHB MAK MEIS2 MKRN3 MLKL NDUFB2 NFKBIB NFKBID RCOR3 RECK RIPPLY1 RIPPLY2 SCNM1 SPRED2 STRA6 TLE5 ZNF330 ZNF417 ZNF564 ZNF587
Entrez ID		4212	4713
HPRD ID		03443	11957
Ensembl ID		ENSG00000134138	ENSG00000099795
Uniprot IDs		A0A024R9L4 B3KP81 B3KPD8 B7Z6F6 O14770	P17568
PDB IDs		3K2A 4XRM 5BNG 5EG0	5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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