MEIS2 and TIMM10B

Data Source:
BioGRID (two hybrid, two hybrid)

		MEIS2	TIMM10B
Description		Meis homeobox 2	translocase of inner mitochondrial membrane 10B
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GO Annotations	Cellular Component	Chromatin Nucleus Perinuclear Region Of Cytoplasm	Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Intermembrane Space Protein Transporter Complex TIM22 Mitochondrial Import Inner Membrane Insertion Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Metal Ion Binding Protein Transporter Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Visual Learning Response To Mechanical Stimulus Embryonic Pattern Specification Animal Organ Morphogenesis Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation	Protein Targeting To Mitochondrion Cell-matrix Adhesion Protein Insertion Into Mitochondrial Inner Membrane
Pathways			Mitochondrial protein import
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Postprandial triglyceride response ( 32603185) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)	Malaria ( 31844061)
Interacting Genes		49 interacting genes: ADRA2C ANTKMT ANXA1 APP ARNT2 BPIFA1 C1orf94 C9orf24 CARTPT CCDC196 CTAG1A CTAG1B DGCR6 FAM136A FAM168A HOXA13 HOXA9 IGFBP6 ITGB3BP KRTAP10-8 KRTAP11-1 KRTAP13-1 KRTAP19-2 KRTAP19-6 KRTAP22-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 MCCD1 NDUFB7 NOTO NUP58 OIP5 OSGIN1 PBX1 PBX4 POU2AF1 POU6F2 PTK6 RBPMS RUSC1 SCT SQSTM1 TBX2 TIMM10B TRIM25 TRIM42 VGLL1 ZNHIT3	5 interacting genes: EIF3F HGS KLHL38 MBD3 MEIS2
Entrez ID		4212	26515
HPRD ID		03443	16242
Ensembl ID		ENSG00000134138	ENSG00000132286
Uniprot IDs		A0A024R9L4 B3KP81 B3KPD8 B7Z6F6 O14770	B2R4A9 Q9Y5J6
PDB IDs		3K2A 4XRM 5BNG 5EG0	7CGP
Enriched GO Terms of Interacting Partners?
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