MEIS2 and SCT

Data Source:
BioGRID (two hybrid)

		MEIS2	SCT
Description		Meis homeobox 2	secretin
Image
GO Annotations	Cellular Component	Chromatin Nucleus Perinuclear Region Of Cytoplasm	Cellular_component Extracellular Region Extracellular Space
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	G Protein-coupled Receptor Binding Signaling Receptor Binding Hormone Activity Protein Binding Digestive Hormone Activity Protein N-terminus Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Visual Learning Response To Mechanical Stimulus Embryonic Pattern Specification Animal Organ Morphogenesis Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation	Diet Induced Thermogenesis G Protein-coupled Receptor Signaling Pathway Brain Development Cellular Water Homeostasis Hippocampus Development Pancreatic Juice Secretion Response To Nutrient Levels Regulation Of Appetite Positive Regulation Of CAMP-mediated Signaling Regulation Of Synaptic Plasticity Embryonic Digestive Tract Development Positive Regulation Of Lipid Catabolic Process Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of Somatostatin Secretion Negative Regulation Of Gastrin-induced Gastric Acid Secretion
Pathways			G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Postprandial triglyceride response ( 32603185) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)
Interacting Genes		49 interacting genes: ADRA2C ANTKMT ANXA1 APP ARNT2 BPIFA1 C1orf94 C9orf24 CARTPT CCDC196 CTAG1A CTAG1B DGCR6 FAM136A FAM168A HOXA13 HOXA9 IGFBP6 ITGB3BP KRTAP10-8 KRTAP11-1 KRTAP13-1 KRTAP19-2 KRTAP19-6 KRTAP22-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 MCCD1 NDUFB7 NOTO NUP58 OIP5 OSGIN1 PBX1 PBX4 POU2AF1 POU6F2 PTK6 RBPMS RUSC1 SCT SQSTM1 TBX2 TIMM10B TRIM25 TRIM42 VGLL1 ZNHIT3	8 interacting genes: HGS HOXA1 MEIS2 MEP1A MEP1B SCTR USHBP1 VIPR1
Entrez ID		4212	6343
HPRD ID		03443	08354
Ensembl ID		ENSG00000134138	ENSG00000070031
Uniprot IDs		A0A024R9L4 B3KP81 B3KPD8 B7Z6F6 O14770	P09683
PDB IDs		3K2A 4XRM 5BNG 5EG0	6WI9 6WZG 7D3S
Enriched GO Terms of Interacting Partners?
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