ARSF and SNRNP70

		ARSF	SNRNP70
Description		arylsulfatase F	small nuclear ribonucleoprotein U1 subunit 70
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Extracellular Exosome	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	Arylsulfatase Activity Metal Ion Binding	RNA Binding MRNA Binding Protein Binding SnRNA Binding U1 SnRNA Binding
	Biological Process		MRNA Splicing, Via Spliceosome Regulation Of ATPase Activity Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Refolding Negative Regulation Of Chaperone-mediated Autophagy
Pathways		Glycosphingolipid metabolism The activation of arylsulfatases	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Systolic blood pressure ( 30224653)
Interacting Genes		2 interacting genes: EP300 SNRNP70	46 interacting genes: APP ARSF CASP3 CDC42 CDKL3 CEP63 CHERP CLK2 CRP CTDP1 DDX17 GEMIN2 GTPBP2 HNRNPA2B1 HTATSF1 IL32 IL7R LRP1 MYC NUDT21 PRKD2 PRMT5 PRPF40A RASGRF1 RELA RNF11 SCAF11 SHBG SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMURF2 SNRPC SRPK1 SRPK2 SRRM4 SRSF1 SRSF10 SRSF2 TOP1 WBP4 ZRANB2
Entrez ID		416	6625
HPRD ID		02049	01617
Ensembl ID		ENSG00000062096	ENSG00000104852
Uniprot IDs		P54793	A0A024QZD5 P08621 Q9UFS1
PDB IDs			2L5I 2L5J 3CW1 3PGW 4PJO 4PKD 6QX9
Enriched GO Terms of Interacting Partners?
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