Description |
SMAD family member 2 |
karyopherin subunit beta 1 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Coronary artery disease in type 1 diabetes ( 29695241)
- Lung cancer in ever smokers ( 28604730)
- Menarche (age at onset) ( 27182965)
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- Asthma ( 31619474)
- Body mass index ( 26426971)
- Glycine levels ( 30837465)
- HDL cholesterol ( 30275531)
- HDL cholesterol levels ( 30698716)
- HDL cholesterol levels in current drinkers ( 30698716)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels ( 30698716)
- LDL cholesterol levels in current drinkers ( 30698716)
- LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Medication use (HMG CoA reductase inhibitors) ( 31015401)
- Multiple sclerosis ( 22190364)
- Optic cup area ( 25631615)
- Simvastatin-induced myopathy ( 31220337)
- Triglyceride levels ( 30698716)
- Triglyceride levels in current drinkers ( 30698716)
- Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
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Interacting Genes |
219 interacting genes:
ABTB1
ACVR1B
AFDN
AKT1
ANAPC10
ANAPC2
ANK3
ANP32B
ANP32E
ANTXR2
AP1B1
ARFGAP3
ARHGEF6
ARL4D
ATP5ME
AXIN1
BAZ1A
BECN1
BPTF
BRCA1
BTBD2
C22orf46
CAMK2A
CAMK2G
CDC16
CDC27
CDC40
CDK2
CDK4
CDK8
CDK9
CISH
COPS5
CORO2A
CREBBP
CSH1
CSH2
CSNK1D
CTNNB1
CUL5
CYLC2
CYP11A1
DAB2
DCAF6
DCUN1D1
DENND2B
DNAJB5
DNAJC7
DOCK8
DVL1
DYNC1H1
E2F4
EEF1A1
EID2
EIF3L
ELAC2
EP300
ERBIN
ESR1
ESR2
FAM161B
FBN2
FBP2
FHL2
FHL3
FOXG1
FOXH1
FOXO3
GATAD2B
GFER
GLI3
GRIPAP1
GSC
GTF2I
HDAC1
HDAC2
HGS
HIPK2
HNF4A
HOXA13
HOXA9
HOXD13
HSD17B3
HUWE1
HYAL2
INSR
IRAK2
ITCH
JUN
KAT2B
KHDRBS1
KPNB1
LAMA5
LATS2
LCK
LEF1
LEMD3
LHX9
LITAF
LMO2
MAP2K1
MAPK1
MAPK3
MAPK8
MAPK9
MECOM
MED15
MED6
MEF2A
MEF2C
MYC
MYOCD
NAGK
NCOA6
NEDD4L
NEDD9
NEFM
NFIA
NFYC
NOTCH4
NUAK2
NUP153
NUP214
OS9
OTUB1
PAK1
PAPOLA
PAPPA
PARD3
PAXIP1
PEX19
PIAS3
PIAS4
PIK3CA
PLIN3
POU2AF1
PPM1A
PPP2R1A
PRKAR1A
PSAP
PSG9
PSMD11
PSMD8
PTMS
RAB34
RAB38
RAN
RANBP6
RANBP9
RARB
RASA1
RASD2
RASL12
RBL1
RHEBL1
RHOA
RHOD
RHOJ
RIT1
RNF123
RNPC3
ROCK1
RPS14
RPS27A
RUNX2
RXRA
SKI
SKIL
SKOR2
SMAD1
SMAD3
SMAD4
SMAD7
SMAD9
SMURF1
SMURF2
SNAPIN
SNIP1
SNRNP70
SNW1
SOD1
SP1
SQSTM1
SRI
ST13
STAG1
STAMBP
STAMBPL1
STRAP
STUB1
SYT1
TBC1D1
TGFBR1
TGFBRAP1
TGIF1
TGM2
TNNT1
TOB1
TP53
TP73
TRIM62
TRMO
TSC2
TUBA1B
UBA52
UBR5
UCHL5
USP9X
WASHC4
XPA
YY1
ZEB1
ZEB2
ZFYVE9
ZMYND11
ZNF41
ZNF510
ZNF8
ZNHIT6
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68 interacting genes:
AMFR
CD99
CHD3
CRBN
CSE1L
CSNK1A1
CUL4A
CUL4B
ELAVL1
EPAS1
EXO1
FGFR1
H1-0
H1-2
IGFBP3
IGFBP5
IPO7
IPO8
ITCH
KPNA1
KPNA2
KPNA3
KPNA4
KPNA6
LINC01554
LYST
MESD
MSL1
MTNR1A
NFATC1
NFYA
NUP153
NUP50
NUP54
NUP62
NUP98
NUTF2
PIAS4
PLCD1
PRKD3
PTEN
PTHLH
PTMA
PTN
PTPN2
RAN
RANBP1
RANBP2
RBX1
RPL5
RUNX1T1
SELENOS
SENP2
SMAD2
SMAD3
SMN1
SMNDC1
SNAPIN
SNUPN
SOX9
SREBF2
SRY
TAF3
TAF8
TERF1
TP53
TUBA1A
UBR5
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Entrez ID |
4087 |
3837 |
HPRD ID |
03221 |
04114 |
Ensembl ID |
ENSG00000175387
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ENSG00000108424
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Uniprot IDs |
B7Z5N5
Q15796
Q53XR6
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B7Z752
Q14974
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PDB IDs |
1DEV
1KHX
1U7V
2LB3
5XOD
5ZOJ
6H3R
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1F59
1IBR
1M5N
1O6O
1O6P
1QGK
1QGR
2P8Q
2Q5D
2QNA
3LWW
3W5K
6N88
6N89
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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