Description |
SMAD family member 2 |
insulin receptor |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Coronary artery disease in type 1 diabetes ( 29695241)
- Lung cancer in ever smokers ( 28604730)
- Menarche (age at onset) ( 27182965)
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Interacting Genes |
219 interacting genes:
ABTB1
ACVR1B
AFDN
AKT1
ANAPC10
ANAPC2
ANK3
ANP32B
ANP32E
ANTXR2
AP1B1
ARFGAP3
ARHGEF6
ARL4D
ATP5ME
AXIN1
BAZ1A
BECN1
BPTF
BRCA1
BTBD2
C22orf46
CAMK2A
CAMK2G
CDC16
CDC27
CDC40
CDK2
CDK4
CDK8
CDK9
CISH
COPS5
CORO2A
CREBBP
CSH1
CSH2
CSNK1D
CTNNB1
CUL5
CYLC2
CYP11A1
DAB2
DCAF6
DCUN1D1
DENND2B
DNAJB5
DNAJC7
DOCK8
DVL1
DYNC1H1
E2F4
EEF1A1
EID2
EIF3L
ELAC2
EP300
ERBIN
ESR1
ESR2
FAM161B
FBN2
FBP2
FHL2
FHL3
FOXG1
FOXH1
FOXO3
GATAD2B
GFER
GLI3
GRIPAP1
GSC
GTF2I
HDAC1
HDAC2
HGS
HIPK2
HNF4A
HOXA13
HOXA9
HOXD13
HSD17B3
HUWE1
HYAL2
INSR
IRAK2
ITCH
JUN
KAT2B
KHDRBS1
KPNB1
LAMA5
LATS2
LCK
LEF1
LEMD3
LHX9
LITAF
LMO2
MAP2K1
MAPK1
MAPK3
MAPK8
MAPK9
MECOM
MED15
MED6
MEF2A
MEF2C
MYC
MYOCD
NAGK
NCOA6
NEDD4L
NEDD9
NEFM
NFIA
NFYC
NOTCH4
NUAK2
NUP153
NUP214
OS9
OTUB1
PAK1
PAPOLA
PAPPA
PARD3
PAXIP1
PEX19
PIAS3
PIAS4
PIK3CA
PLIN3
POU2AF1
PPM1A
PPP2R1A
PRKAR1A
PSAP
PSG9
PSMD11
PSMD8
PTMS
RAB34
RAB38
RAN
RANBP6
RANBP9
RARB
RASA1
RASD2
RASL12
RBL1
RHEBL1
RHOA
RHOD
RHOJ
RIT1
RNF123
RNPC3
ROCK1
RPS14
RPS27A
RUNX2
RXRA
SKI
SKIL
SKOR2
SMAD1
SMAD3
SMAD4
SMAD7
SMAD9
SMURF1
SMURF2
SNAPIN
SNIP1
SNRNP70
SNW1
SOD1
SP1
SQSTM1
SRI
ST13
STAG1
STAMBP
STAMBPL1
STRAP
STUB1
SYT1
TBC1D1
TGFBR1
TGFBRAP1
TGIF1
TGM2
TNNT1
TOB1
TP53
TP73
TRIM62
TRMO
TSC2
TUBA1B
UBA52
UBR5
UCHL5
USP9X
WASHC4
XPA
YY1
ZEB1
ZEB2
ZFYVE9
ZMYND11
ZNF41
ZNF510
ZNF8
ZNHIT6
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86 interacting genes:
ACP1
ADRB2
AHSG
ARF1
ARHGAP26
CALM1
CALM2
CALM3
CAV1
CAV3
CBL
CCDC88A
CEACAM1
CRK
CRKL
CSK
DOK1
DOK4
DOK5
DUSP18
DUSP19
ENPP1
ERBB2
FABP4
FRS2
GAB1
GRB10
GRB14
GRB7
HRAS
IGF1R
IGF2
INS
INSRR
IRF7
IRS1
IRS2
JAK1
JAK2
KHDRBS1
KRT27
KRT31
MAD2L1
MAPK3
MARCHF1
PIK3R1
PIK3R3
PLCG1
PRKCA
PRKCD
PTK2
PTPN1
PTPN11
PTPN12
PTPN2
PTPN6
PTPRC
PTPRF
PTPRR
RACK1
RAF1
RASA1
SH2B1
SH2B2
SHC1
SMAD2
SNX1
SNX2
SNX4
SNX6
SOCS1
SOCS2
SOCS3
SOCS6
SORBS1
SRC
STAT5A
STAT5B
STUB1
STYX
SYNCRIP
TEAD1
TRIM72
VAV1
VAV3
YWHAB
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Entrez ID |
4087 |
3643 |
HPRD ID |
03221 |
00975 |
Ensembl ID |
ENSG00000175387
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ENSG00000171105
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Uniprot IDs |
B7Z5N5
Q15796
Q53XR6
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P06213
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PDB IDs |
1DEV
1KHX
1U7V
2LB3
5XOD
5ZOJ
6H3R
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1GAG
1I44
1IR3
1IRK
1P14
1RQQ
2AUH
2B4S
2HR7
2MFR
2Z8C
3BU3
3BU5
3BU6
3EKK
3EKN
3ETA
3W11
3W12
3W13
4IBM
4OGA
4XLV
4XSS
4XST
4ZXB
5E1S
5HHW
5J3H
5KQV
5U1M
6HN4
6HN5
6PXV
6PXW
6SOF
6VEP
6VEQ
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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