VGLL3 and CTRC

Data Source:
BioGRID (two hybrid)

		VGLL3	CTRC
Description		vestigial like family member 3	chymotrypsin C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region
	Molecular Function		Serine-type Endopeptidase Activity Protein Binding Peptidase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Proteolysis Cellular Calcium Ion Homeostasis Cobalamin Metabolic Process
Pathways			Cobalamin (Cbl, vitamin B12) transport and metabolism
Drugs
Diseases			Tropical calcific pancreatitis Hereditary pancreatitis; Hereditary chronic pancreatitis
GWAS		Adventurousness ( 30643258) Breast cancer ( 29059683) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) Menarche (age at onset) ( 27182965 21102462) Metabolite levels ( 23823483) Molybdenum levels ( 26025379) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Prostate cancer ( 31562322 26443449) Pubertal anthropometrics ( 23449627) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Triglyceride levels ( 32203549)	Alcoholic chronic pancreatitis ( 28754779)
Interacting Genes		65 interacting genes: CDPF1 CERCAM CNFN CTRC CYSRT1 DTX2 ESM1 FAM168B FRS3 HGS INCA1 KPRP KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP13-2 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP4-11 KRTAP4-2 KRTAP5-11 KRTAP5-6 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LASP1 LENG8 MDFI MYO15B OXER1 PCSK5 PITX1 PITX2 PLA2G10 POGZ POU2AF1 PRR22 RBPMS RUSC1 SMARCC1 SMOC1 TBX15 TEAD1 TEAD2 TEAD3 TEAD4 TEX37 TRIM42 TSC1 TSPAN4 UFSP1 YPEL3 ZNF34	20 interacting genes: CYSRT1 GIPC2 KRT34 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP3-1 KRTAP6-2 KRTAP9-2 MDFI NEDD8 NFKBID PHKG1 SERPINA3 SPINK1 ST13 TEX37 UBC VGLL3
Entrez ID		389136	11330
HPRD ID		13431	03242
Ensembl ID		ENSG00000206538	ENSG00000162438
Uniprot IDs		A8MV65	Q99895
PDB IDs			4H4F
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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