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NOTCH2NLA and GSTP1
Data Source:
BioGRID
(two hybrid, two hybrid)
NOTCH2NLA
GSTP1
Description
notch 2 N-terminal like A
glutathione S-transferase pi 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Cytoplasm
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Vesicle
Secretory Granule Lumen
Extracellular Exosome
TRAF2-GSTP1 Complex
Ficolin-1-rich Granule Lumen
Molecular Function
Notch Binding
Calcium Ion Binding
Protein Binding
Glutathione Transferase Activity
Glutathione Peroxidase Activity
Fatty Acid Binding
Protein Binding
Drug Binding
JUN Kinase Binding
Kinase Regulator Activity
S-nitrosoglutathione Binding
Dinitrosyl-iron Complex Binding
Glutathione Binding
Nitric Oxide Binding
Biological Process
Notch Signaling Pathway
Cerebral Cortex Development
Cell Differentiation
Positive Regulation Of Notch Signaling Pathway
Response To Reactive Oxygen Species
Negative Regulation Of Acute Inflammatory Response
Negative Regulation Of Protein Kinase Activity
Prostaglandin Metabolic Process
Glutathione Metabolic Process
Xenobiotic Metabolic Process
Central Nervous System Development
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Oligodendrocyte Development
Animal Organ Regeneration
Response To Estradiol
Negative Regulation Of Interleukin-1 Beta Production
Negative Regulation Of Tumor Necrosis Factor Production
Cellular Response To Insulin Stimulus
Regulation Of Stress-activated MAPK Cascade
Negative Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Superoxide Anion Generation
Response To L-ascorbic Acid
Cellular Response To Oxidative Stress
Common Myeloid Progenitor Cell Proliferation
Nitric Oxide Storage
Negative Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Amino Acid
Neutrophil Degranulation
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of MAPK Cascade
Negative Regulation Of JUN Kinase Activity
Linoleic Acid Metabolic Process
Response To Ethanol
Negative Regulation Of Fibroblast Proliferation
Hepoxilin Biosynthetic Process
Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process
Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Leukocyte Proliferation
Cellular Response To Lipopolysaccharide
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Cell-matrix Adhesion
Negative Regulation Of Monocyte Chemotactic Protein-1 Production
Negative Regulation Of Smooth Muscle Cell Chemotaxis
Cellular Oxidant Detoxification
Glutathione Derivative Biosynthetic Process
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Glutathione conjugation
Detoxification of Reactive Oxygen Species
Neutrophil degranulation
Drugs
Glutathione
Troglitazone
Clozapine
Etacrynic acid
Clomipramine
(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene
S-Hydroxycysteine
Cibacron Blue
Glutathione sulfonic acid
Glutathione disulfide
Deoxycholic acid
S-(4-nitrobenzyl)glutathione
2-(N-morpholino)ethanesulfonic acid
S-Hexylglutathione
Carbocisteine
Canfosfamide
Ezatiostat
Exisulind
S-NONYL-CYSTEINE
S-(4-BROMOBENZYL)CYSTEINE
Curcumin
Dinitrochlorobenzene
Hypericin
Curcumin sulfate
Diseases
Prostate cancer
GWAS
Blood protein levels (
29875488
)
Refractive error (
32231278
)
Interacting Genes
357 interacting genes:
ACY3
ADAM12
ADAMTSL3
ADAMTSL4
ADAMTSL5
ADCK5
AGXT
ALDH16A1
ALDH3B1
ALPI
ALPP
ANKS1A
AQP1
AQP5
ARID3A
ASPSCR1
ATG9A
ATP5F1D
BCAM
BCL6B
BLCAP
BMP7
BRME1
C11orf87
C5orf60
CA6
CARHSP1
CATSPER1
CCDC26
CCDC93
CCER1
CD164
CDK5R1
CELF5
CERK
CHCHD3
CHDH
CHIC2
CHRD
CHRNG
CLDN2
CLEC18A
CNNM3
COL8A1
CRACR2A
CRCT1
CREB5
CRH
CRY2
CSF1
CST2
CST9L
CTNNBIP1
CTSG
CTSZ
CXCL16
CXCL5
CYHR1
CYP21A2
CYSRT1
DAGLB
DALRD3
DBH
DGCR6
DGKQ
DHRS1
DMRT3
DNAL4
DOCK2
DRD5
EFNA3
EIF4E2
ELANE
EMC7
EPHB6
ESR2
F10
FAAH
FADS2
FAM124B
FAM221A
FAM71C
FAM71E2
FAM74A4
FAM90A1
FARS2
FASLG
FBXL18
FBXW5
FOXB1
FRS3
FTHL17
FZD10
GABRD
GATA2
GEM
GFOD1
GIP
GLP1R
GLRX3
GLYAT
GNAI2
GNE
GNMT
GSTP1
GTF3C5
H2AC15
HAPLN2
HBA1
HBA2
HBZ
HCK
HHEX
HOXA1
HOXB9
HOXC8
HPCAL1
HSBP1
HSD3B7
HSPA12B
HSPBP1
HSPD1
ICAM4
IFI30
IL10
IL2RG
INO80B
INPP5D
INS
ITGB2
ITGB4
ITGB5
JOSD1
KCNS2
KCTD15
KIF1A
KLHL38
KLK8
KPRP
KRT20
KRT83
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP13-2
KRTAP13-3
KRTAP13-4
KRTAP2-3
KRTAP2-4
KRTAP26-1
KRTAP3-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP4-7
KRTAP5-11
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LCE1A
LCE1B
LCE1D
LCE1E
LCE1F
LCE2B
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LIMS2
LIN7A
LINC00526
LINC00656
LMNTD2
LMO2
LNX1
LONRF3
LRCH4
LRFN4
LYVE1
MACO1
MAPKBP1
MARK4
MATN3
MELTF
MFSD13A
MOS
MRGBP
MRPL40
MTA1
MVP
MXD3
MXI1
MYO15B
MYPOP
NAB2
NAXD
NECTIN2
NECTIN3
NEDD9
NEU2
NMU
NMUR2
NPBWR2
NPDC1
NPPB
NR1D2
NTM
NTN4
NUBP2
OLFM2
OTX1
P2RX4
P2RX7
P2RY6
PCED1A
PCED1B
PCSK5
PDE9A
PGAP6
PGLS
PHLDA1
PID1
PIGS
PLEKHN1
PLPP2
PLSCR4
POLR2G
POM121L8P
POMGNT2
PRF1
PRKAA2
PRPF31
PRPS2
PRR35
PSMA1
PSMG2
PTGER3
PTK7
PTPMT1
PTPN23
PVR
QPRT
R3HDM2
RAB3IL1
RAMP3
RASD1
RCHY1
RECK
RET
RGL2
RNF111
RPS19BP1
RPS28
RTN4RL1
SCNM1
SDCBP
SELENOM
SEMA3B
SEMA4C
SHFL
SLC22A23
SLC22A5
SLC23A1
SLC25A10
SLC25A6
SLC43A2
SLC5A5
SLC6A20
SMARCD2
SMARCE1
SMCP
SMOC1
SNAI1
SPATA24
SPATA8
SPG7
SPINK2
SPPL2C
SPRY1
STAC
STK16
TAPBPL
TBC1D10C
TBC1D16
TCAF1
TEDC2
THAP7
THEMIS2
TINAGL1
TLE5
TMEFF2
TMEM150A
TMEM231
TMEM41A
TMIE
TNIP3
TNK2
TNP2
TNS2
TRAPPC14
TRIM27
TRIM42
TROAP
TRPV6
TSPAN4
TTPA
TXNDC5
UBQLN4
UTP23
UXT
VASN
WDR25
WT1-AS
XCL2
YIPF3
ZDHHC1
ZFYVE21
ZNF124
ZNF319
ZNF32
ZNF330
ZNF408
ZNF414
ZNF417
ZNF439
ZNF440
ZNF446
ZNF497
ZNF580
ZNF581
ZNF587
ZNF648
ZNF672
ZNF688
ZNF786
ZNF837
35 interacting genes:
ADAMTSL4
APPBP2
CARD10
CYSRT1
FANCC
FHL5
HOXA1
KRT31
KRT33B
KRT34
KRT83
KRTAP1-1
KRTAP1-3
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP3-1
KRTAP3-3
KRTAP6-2
LRP2BP
MAPK8
MLH1
MTUS2
NBPF19
NOTCH2NLA
PNO1
PRDX6
PTN
SCAF1
SH3GLB1
SUMO4
TGM1
TGM2
TRAF2
ZNF655
Entrez ID
388677
2950
HPRD ID
14833
00614
Ensembl ID
ENSG00000264343
ENSG00000084207
Uniprot IDs
P0DPK4
Q7Z3S9
P09211
V9HWE9
PDB IDs
10GS
11GS
12GS
13GS
14GS
16GS
17GS
18GS
19GS
1AQV
1AQW
1AQX
1EOG
1EOH
1GSS
1KBN
1LBK
1MD3
1MD4
1PGT
1PX6
1PX7
1ZGN
20GS
22GS
2A2R
2A2S
2GSS
2J9H
2PGT
3CSH
3CSI
3CSJ
3DD3
3DGQ
3GSS
3GUS
3HJM
3HJO
3HKR
3IE3
3KM6
3KMN
3KMO
3N9J
3PGT
4GSS
4PGT
5DAK
5DAL
5DCG
5DDL
5DJL
5DJM
5GSS
5J41
5JCW
5L6X
5X79
6AP9
6GSS
6Y1E
7GSS
8GSS
9GSS
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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