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GSTP1 and HOXA1
Data Source:
BioGRID
(two hybrid)
GSTP1
HOXA1
Description
glutathione S-transferase pi 1
homeobox A1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Vesicle
Secretory Granule Lumen
Extracellular Exosome
TRAF2-GSTP1 Complex
Ficolin-1-rich Granule Lumen
Chromatin
Nucleus
Molecular Function
Glutathione Transferase Activity
Glutathione Peroxidase Activity
Fatty Acid Binding
Protein Binding
Drug Binding
JUN Kinase Binding
Kinase Regulator Activity
S-nitrosoglutathione Binding
Dinitrosyl-iron Complex Binding
Glutathione Binding
Nitric Oxide Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Identical Protein Binding
Sequence-specific DNA Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Response To Reactive Oxygen Species
Negative Regulation Of Acute Inflammatory Response
Negative Regulation Of Protein Kinase Activity
Prostaglandin Metabolic Process
Glutathione Metabolic Process
Xenobiotic Metabolic Process
Central Nervous System Development
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Oligodendrocyte Development
Animal Organ Regeneration
Response To Estradiol
Negative Regulation Of Interleukin-1 Beta Production
Negative Regulation Of Tumor Necrosis Factor Production
Cellular Response To Insulin Stimulus
Regulation Of Stress-activated MAPK Cascade
Negative Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Superoxide Anion Generation
Response To L-ascorbic Acid
Cellular Response To Oxidative Stress
Common Myeloid Progenitor Cell Proliferation
Nitric Oxide Storage
Negative Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Amino Acid
Neutrophil Degranulation
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of MAPK Cascade
Negative Regulation Of JUN Kinase Activity
Linoleic Acid Metabolic Process
Response To Ethanol
Negative Regulation Of Fibroblast Proliferation
Hepoxilin Biosynthetic Process
Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process
Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Leukocyte Proliferation
Cellular Response To Lipopolysaccharide
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Cell-matrix Adhesion
Negative Regulation Of Monocyte Chemotactic Protein-1 Production
Negative Regulation Of Smooth Muscle Cell Chemotaxis
Cellular Oxidant Detoxification
Glutathione Derivative Biosynthetic Process
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Regulation Of Transcription By RNA Polymerase II
Multicellular Organism Development
Sensory Perception Of Sound
Optokinetic Behavior
Anatomical Structure Morphogenesis
Abducens Nerve Formation
Outer Ear Morphogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Embryonic Neurocranium Morphogenesis
Inner Ear Development
Artery Morphogenesis
Regulation Of Behavior
Cognition
Neuromuscular Process
Artery Development
Semicircular Canal Formation
Cochlea Development
Cochlea Morphogenesis
Pathways
Glutathione conjugation
Detoxification of Reactive Oxygen Species
Neutrophil degranulation
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Glutathione
Troglitazone
Clozapine
Etacrynic acid
Clomipramine
(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene
S-Hydroxycysteine
Cibacron Blue
Glutathione sulfonic acid
Glutathione disulfide
Deoxycholic acid
S-(4-nitrobenzyl)glutathione
2-(N-morpholino)ethanesulfonic acid
S-Hexylglutathione
Carbocisteine
Canfosfamide
Ezatiostat
Exisulind
S-NONYL-CYSTEINE
S-(4-BROMOBENZYL)CYSTEINE
Curcumin
Dinitrochlorobenzene
Hypericin
Curcumin sulfate
Diseases
Prostate cancer
Bosley-Salih-Alorainy syndrome and Athabascan brainstem dysgenesis syndrome
GWAS
Blood protein levels (
29875488
)
Refractive error (
32231278
)
Chronic venous disease (
28374850
)
Macular thickness (
30535121
)
Multiple sclerosis (
31604244
)
Small cell lung carcinoma (
28604730
)
Tonsillectomy (
27182965
28928442
)
Interacting Genes
35 interacting genes:
ADAMTSL4
APPBP2
CARD10
CYSRT1
FANCC
FHL5
HOXA1
KRT31
KRT33B
KRT34
KRT83
KRTAP1-1
KRTAP1-3
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP3-1
KRTAP3-3
KRTAP6-2
LRP2BP
MAPK8
MLH1
MTUS2
NBPF19
NOTCH2NLA
PNO1
PRDX6
PTN
SCAF1
SH3GLB1
SUMO4
TGM1
TGM2
TRAF2
ZNF655
292 interacting genes:
ADAM12
ADAMTSL4
AGXT
ALG13
ALPP
AMMECR1
AMOT
ANKS1A
ARID5A
ARMC7
ATG9B
ATP23
BAG4
BAHD1
BATF2
BHLHB9
BLCAP
BLZF1
BSCL2
BUD31
C11orf1
C11orf16
CATSPER1
CCDC120
CCDC33
CCN3
CCN4
CCN5
CCNK
CD164
CDPF1
CERCAM
CFP
CHIC2
CHRD
CHRDL2
CNFN
CNNM3
COL8A1
CREB5
CUTA
CXCL16
CYHR1
CYP21A2
CYSRT1
DOCK2
DOCK3
DOK3
DTX2
DUSP10
DUSP22
EFEMP1
EFEMP2
EGFL7
ENKD1
EPDR1
ESM1
ESR2
EVA1B
FAAP100
FAM219B
FAM221A
FBLN1
FHL3
FHL5
FOXH1
FOXN1
FRS3
FST
FUCA2
GAS8
GATA1
GCM2
GDF15
GNE
GP9
GPS2
GRN
GSTP1
GUCD1
HEXB
HEXIM2
HEY2
HOXB9
HR
HSD3B7
ID3
IGFL1
IGFN1
INCA1
INO80B
IRX6
ITGB4
KCTD9
KDM1A
KPRP
KRT31
KRT33B
KRT34
KRT35
KRT37
KRT38
KRT40
KRT81
KRT82
KRT83
KRTAP1-1
KRTAP1-3
KRTAP1-5
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-4
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP13-2
KRTAP13-3
KRTAP13-4
KRTAP15-1
KRTAP19-6
KRTAP19-7
KRTAP2-3
KRTAP2-4
KRTAP23-1
KRTAP26-1
KRTAP3-2
KRTAP3-3
KRTAP4-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP4-7
KRTAP5-11
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP6-1
KRTAP6-2
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LASP1
LCE1A
LCE1B
LCE1C
LCE1D
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3C
LCE3E
LCE4A
LCE5A
LGALS13
LGALS4
LMX1B
LNX1
LONRF1
LPXN
MACO1
MAPKBP1
MDFI
MFAP2
MGAT5B
MKRN3
MYO15B
MYPOP
N4BP2L2
NBPF19
NCK2
NECTIN2
NEDD9
NEK6
NELL2
NFKBID
NOTCH2NLA
NR1D2
NTN4
NXF1
ODF1
OIT3
P2RY6
PAX6
PBX2
PCSK5
PCYOX1
PHETA1
PIK3R1
PIN1
PITX1
PITX2
PKNOX1
PLEKHN1
PLLP
PLSCR1
PLSCR2
PLSCR3
PLSCR4
PPP1R32
PRICKLE4
PRMT6
PROP1
PSMB1
PTH1R
PVR
QARS1
RALGDS
RANBP3
RBCK1
RBP3
RBPMS
RCHY1
RGS17
RGS19
RGS20
RNF208
RSPO2
RTN4R
SCT
SDCBP
SIVA1
SLC15A3
SLC23A1
SLIT1
SLPI
SNRPB
SNRPC
SPATA12
SPATA18
SPRY1
SPRY2
SPRY3
SPRY4
SSC4D
SSUH2
STX11
SUV39H1
TBC1D10C
TBX15
TCF19
TCF3
TEKT4
TEKT5
TGFB1
TGM7
THAP7
TLE5
TNS2
TRAF1
TRAF2
TRAF4
TRAPPC6A
TRIM42
TRIM55
TRIM63
TRIM8
TRIP6
TSPAN4
UBL5
UNKL
VASN
VWC2
VWC2L
WDR83
WWOX
YIPF3
YPEL3
ZBTB16
ZIM2
ZMAT1
ZNF417
ZNF587
ZNF688
ZNF774
ZNF837
ZNF843
Entrez ID
2950
3198
HPRD ID
00614
00843
Ensembl ID
ENSG00000084207
ENSG00000105991
Uniprot IDs
P09211
V9HWE9
P49639
PDB IDs
10GS
11GS
12GS
13GS
14GS
16GS
17GS
18GS
19GS
1AQV
1AQW
1AQX
1EOG
1EOH
1GSS
1KBN
1LBK
1MD3
1MD4
1PGT
1PX6
1PX7
1ZGN
20GS
22GS
2A2R
2A2S
2GSS
2J9H
2PGT
3CSH
3CSI
3CSJ
3DD3
3DGQ
3GSS
3GUS
3HJM
3HJO
3HKR
3IE3
3KM6
3KMN
3KMO
3N9J
3PGT
4GSS
4PGT
5DAK
5DAL
5DCG
5DDL
5DJL
5DJM
5GSS
5J41
5JCW
5L6X
5X79
6AP9
6GSS
6Y1E
7GSS
8GSS
9GSS
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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