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GSTP1 and ADAMTSL4
Data Source:
BioGRID
(two hybrid)
GSTP1
ADAMTSL4
Description
glutathione S-transferase pi 1
ADAMTS like 4
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Vesicle
Secretory Granule Lumen
Extracellular Exosome
TRAF2-GSTP1 Complex
Ficolin-1-rich Granule Lumen
Interstitial Matrix
Endoplasmic Reticulum Lumen
Extracellular Matrix
Collagen-containing Extracellular Matrix
Molecular Function
Glutathione Transferase Activity
Glutathione Peroxidase Activity
Fatty Acid Binding
Protein Binding
Drug Binding
JUN Kinase Binding
Kinase Regulator Activity
S-nitrosoglutathione Binding
Dinitrosyl-iron Complex Binding
Glutathione Binding
Nitric Oxide Binding
Protease Binding
Metalloendopeptidase Activity
Protein Binding
Biological Process
Response To Reactive Oxygen Species
Negative Regulation Of Acute Inflammatory Response
Negative Regulation Of Protein Kinase Activity
Prostaglandin Metabolic Process
Glutathione Metabolic Process
Xenobiotic Metabolic Process
Central Nervous System Development
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Oligodendrocyte Development
Animal Organ Regeneration
Response To Estradiol
Negative Regulation Of Interleukin-1 Beta Production
Negative Regulation Of Tumor Necrosis Factor Production
Cellular Response To Insulin Stimulus
Regulation Of Stress-activated MAPK Cascade
Negative Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Superoxide Anion Generation
Response To L-ascorbic Acid
Cellular Response To Oxidative Stress
Common Myeloid Progenitor Cell Proliferation
Nitric Oxide Storage
Negative Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Amino Acid
Neutrophil Degranulation
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of MAPK Cascade
Negative Regulation Of JUN Kinase Activity
Linoleic Acid Metabolic Process
Response To Ethanol
Negative Regulation Of Fibroblast Proliferation
Hepoxilin Biosynthetic Process
Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process
Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Leukocyte Proliferation
Cellular Response To Lipopolysaccharide
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Cell-matrix Adhesion
Negative Regulation Of Monocyte Chemotactic Protein-1 Production
Negative Regulation Of Smooth Muscle Cell Chemotaxis
Cellular Oxidant Detoxification
Glutathione Derivative Biosynthetic Process
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Epithelial Cell Development
Proteolysis
Apoptotic Process
Extracellular Matrix Organization
Positive Regulation Of Apoptotic Process
Pathways
Glutathione conjugation
Detoxification of Reactive Oxygen Species
Neutrophil degranulation
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins
Drugs
Glutathione
Troglitazone
Clozapine
Etacrynic acid
Clomipramine
(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene
S-Hydroxycysteine
Cibacron Blue
Glutathione sulfonic acid
Glutathione disulfide
Deoxycholic acid
S-(4-nitrobenzyl)glutathione
2-(N-morpholino)ethanesulfonic acid
S-Hexylglutathione
Carbocisteine
Canfosfamide
Ezatiostat
Exisulind
S-NONYL-CYSTEINE
S-(4-BROMOBENZYL)CYSTEINE
Curcumin
Dinitrochlorobenzene
Hypericin
Curcumin sulfate
Diseases
Prostate cancer
Ectopia lentis
GWAS
Blood protein levels (
29875488
)
Refractive error (
32231278
)
Asthma (
32296059
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Coronary artery disease (
29212778
)
Cortical surface area (min-P) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (min-P) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Migraine (
27322543
)
Refractive error (
32231278
)
Rhegmatogenous retinal detachment (
23585552
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
35 interacting genes:
ADAMTSL4
APPBP2
CARD10
CYSRT1
FANCC
FHL5
HOXA1
KRT31
KRT33B
KRT34
KRT83
KRTAP1-1
KRTAP1-3
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP3-1
KRTAP3-3
KRTAP6-2
LRP2BP
MAPK8
MLH1
MTUS2
NBPF19
NOTCH2NLA
PNO1
PRDX6
PTN
SCAF1
SH3GLB1
SUMO4
TGM1
TGM2
TRAF2
ZNF655
209 interacting genes:
ADAM12
ADAMTSL5
ALPP
AMMECR1
APOL6
AQP1
ARNT2
ASPSCR1
ATG9A
BAG4
BANF2
BOLA2
BOLA2B
BRME1
CATSPER1
CBX3
CCDC26
CFAP206
CHCHD2
CHERP
CHIC2
CHRD
CHRNG
CLEC18A
COL8A1
CPNE7
CREB5
CST2
CTSB
CXCL16
CYP2S1
CYSRT1
DGCR6
DGCR6L
DIP2A
DLK2
DNPEP
DSCR8
EFEMP2
EIF4E2
EPDR1
ERCC3
EXOSC5
FAH
FAM124B
FARS2
FBLN1
FBXO17
FBXW5
FHL3
FKBP1B
FLNA
FRS3
GATA2
GIP
GLRX3
GLYCTK
GMCL2
GNE
GNG13
GNMT
GOLGA8EP
GSTP1
GUCD1
HEXIM2
HGF
HNRNPLL
HOXA1
HOXC8
HSD3B7
INS
IP6K1
ITGB2
ITGB4
JOSD1
KCTD7
KCTD9
KIF1A
KLHL38
KRTAP1-1
KRTAP1-5
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-3
KRTAP19-2
KRTAP21-2
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-7
KRTAP5-9
KRTAP6-2
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-4
LCE1A
LCE1B
LCE1C
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LCE3E
LCE4A
LGALS14
LHX4
LINC00671
LMO1
LMO2
LMO4
LNX1
LONRF1
LRFN4
LRRC29
MAGOHB
MAPKBP1
MGAT5B
MID2
MKRN3
MORN3
MVP
MYLIP
MYO15B
NATD1
NBPF19
NEK8
NFKBID
NMUR2
NOTCH2NLA
NR4A3
NTAQ1
NTF4
NTN4
NUFIP2
OLFM3
OTX1
PCSK5
PID1
PIN1
PKN1
PLSCR1
PLSCR4
POLD1
POLR1C
POU4F2
PRKAB2
PRR19
PTGER3
PTPMT1
QPRT
R3HDM2
RAB2B
RCHY1
RGL2
RHOJ
RPS19BP1
RUNX1T1
SALL2
SCNM1
SHFL
SLC13A5
SLC23A1
SLC6A20
SLIT1
SMARCC1
SORBS3
SPATA8
SPINK2
SPRY1
SPRY2
STK16
SUSD6
TAPBPL
TCEA2
TFAP2D
TGFB1
THAP6
TMEM150A
TMSB4XP6
TOP3B
TRIM42
TRIM55
TRIM63
TRIP6
TSSK3
TUBGCP4
USP21
VASN
VENTX
VWC2
ZFHX2
ZNF330
ZNF414
ZNF417
ZNF587
Entrez ID
2950
54507
HPRD ID
00614
18237
Ensembl ID
ENSG00000084207
ENSG00000143382
Uniprot IDs
P09211
V9HWE9
A0A669KBE7
B7ZMJ3
Q6UY14
Q9UFG7
PDB IDs
10GS
11GS
12GS
13GS
14GS
16GS
17GS
18GS
19GS
1AQV
1AQW
1AQX
1EOG
1EOH
1GSS
1KBN
1LBK
1MD3
1MD4
1PGT
1PX6
1PX7
1ZGN
20GS
22GS
2A2R
2A2S
2GSS
2J9H
2PGT
3CSH
3CSI
3CSJ
3DD3
3DGQ
3GSS
3GUS
3HJM
3HJO
3HKR
3IE3
3KM6
3KMN
3KMO
3N9J
3PGT
4GSS
4PGT
5DAK
5DAL
5DCG
5DDL
5DJL
5DJM
5GSS
5J41
5JCW
5L6X
5X79
6AP9
6GSS
6Y1E
7GSS
8GSS
9GSS
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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