Description |
keratin associated protein 6-2 |
estrogen receptor 2 |
Image |
No pdb structure |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Diethylstilbestrol
- Conjugated estrogens
- Progesterone
- Raloxifene
- Estrone
- Tamoxifen
- Estradiol
- Trilostane
- Estramustine
- Oxybenzone
- Genistein
- Prasterone
- Benzophenone
- Phthalic Acid
- Pyrazole
- Para-Mercury-Benzenesulfonic Acid
- Naringenin
- ICI-164384
- 5-Alpha-Androstane-3-Beta,17beta-Diol
- 4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol
- Quercetin
- Afimoxifene
- Estriol
- Estrone sulfate
- MF101
- CHF 4227
- TAS-108
- Lasofoxifene
- Arzoxifene
- Bazedoxifene
- Prinaberel
- ERB-196
- [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
- 4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL
- 2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL
- 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL
- (3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol
- 1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL
- 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME
- 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE
- 3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE
- 3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL
- (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- 17alpha-Estriol
- (9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one
- Erteberel
- (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL
- Eugenol
- Octocrylene
- Enzacamene
- Equol
- 2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol
- Estradiol acetate
- Estradiol benzoate
- Estradiol cypionate
- Estradiol dienanthate
- Estradiol valerate
- Estriol tripropionate
- Fluoroestradiol F-18
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Diseases |
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GWAS |
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- anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
- Atrial fibrillation ( 30061737)
- Chronotype ( 30696823)
- Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
- Depression ( 29700475)
- Hematocrit ( 32888494 27863252)
- Hemoglobin ( 32888494)
- Hemoglobin concentration ( 27863252)
- Hemoglobin levels ( 32327693)
- Metabolite levels ( 23823483)
- Prostate cancer ( 26443449)
- Red blood cell count ( 32888494 27863252)
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Interacting Genes |
185 interacting genes:
ADAM12
ADAMTSL4
ANAPC11
ANKS1A
ANXA11
APOBEC1
AQP1
ARID5A
ATG9A
ATN1
ATPAF2
BEX2
BHLHE40
C10orf55
C1orf94
C20orf85
C6orf15
CAMK2A
CAMK2B
CASC3
CATSPER1
CCDC120
CCDC17
CCDC28A-AS1
CCER1
CCNK
CELF5
CERCAM
CERK
CFP
CHIC2
COL8A1
CREB5
CTRC
CYSRT1
DAZAP2
DHRS1
DMRT3
ENKD1
ESR2
FAAP20
FAM166B
FAM168A
FAM214B
FAM83A
FOXD2
FOXD4L1
FOXD4L3
FOXP3
FRS3
GALT
GATA3
GCM2
GLIS2
GLYCTK
GNE
GPS2
GRINA
GRN
GSTP1
HAPLN2
HELT
HEY1
HEY2
HEYL
HHEX
HOXA1
HOXB9
HOXC8
HOXC9
HSF4
HYAL2
IGFN1
INCA1
INO80B
ITGB4
KLHL38
KPRP
KRT83
KRTAP11-1
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP15-1
KRTAP19-5
KRTAP26-1
KRTAP3-3
KRTAP4-11
KRTAP4-12
KRTAP6-1
KRTAP6-3
LASP1
LCE2B
LCE2D
LCE5A
LETM1
LGALS9C
LRFN4
LRRC41
LYVE1
MEIS2
MGAT5B
MKRN3
NAF1
NDUFA9
NEU4
NFKBID
NID2
NPBWR2
NR1D2
NSD1
OLIG3
OTX1
PATL1
PATZ1
PAX3
PDP1
PHLDA1
PITX1
PKD2
PLEKHN1
PLSCR4
POGZ
POU5F2
PPP1R32
PRR13
PRR3
PRR30
PRR35
RASD1
RBFOX2
RBPMS2
RERE
RHOXF2
RNF38
ROR2
RTP5
RUNX1T1
RUSC1
SAMD7
SHARPIN
SIAH3
SMAP2
SMARCC1
SMN1
SMN2
SMUG1
SNRPB
SNRPC
SPAG8
SPATA8
TBX6
TCF7L2
TEKT3
TEKT4
TEKT5
TENT5B
TENT5D
TEPSIN
TEX37
TFAP2D
TLE5
TLX2
TLX3
TNIP1
TOLLIP
TPRX1
TRIP13
TSGA10IP
TSPAN4
TSPYL6
VAC14
VENTX
VGLL3
VPS37C
YPEL3
ZBTB32
ZC3H10
ZIC1
ZNF414
ZNF503
ZNF581
ZNF683
ZNF843
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104 interacting genes:
AGR3
AKAP13
AKT1
ARID5A
BCAS2
CALM1
CALM2
CALM3
CASC3
CASZ1
CCNC
CDK8
CYSRT1
DAP3
DDX54
DKK3
DNMT3L
DNTTIP2
EP300
ESR1
HOXA1
IL13RA2
IL24
ITIH5
JMJD1C
KAT5
KLK9
KPNA3
KPRP
KRTAP6-2
LCK
LRATD2
MAD2L1
MAPK1
MAPK11
MED1
MED10
MED12
MED14
MED16
MED17
MED20
MED21
MED23
MED24
MED6
MED7
MEOX2
MKNK2
MMS19
MRC2
MSH2
NCOA1
NCOA2
NCOA3
NCOA6
NCOA7
NCOR1
NCOR2
NFKBIB
NFKBID
NOTCH2NLA
NR0B1
NR0B2
NRIP1
OXT
PELP1
PIAS1
PIAS2
PIAS3
PLSCR1
PNRC1
PNRC2
PPARGC1A
PPP5C
PRMT2
PRSS50
PSMC3IP
PSMC5
RBFOX2
RBM39
REXO4
RFX6
SERPINH1
SMAD2
SMAD3
SMAD4
SMARCE1
SP1
SRA1
SRC
SREBF1
STAT5A
TFF1
TRAM1
TRIM24
TRIM59
TRIP4
TXNRD1
WIPI1
YWHAH
YWHAQ
ZBTB17
ZNHIT3
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Entrez ID |
337967 |
2100 |
HPRD ID |
11219 |
03390 |
Ensembl ID |
ENSG00000186930
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ENSG00000140009
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Uniprot IDs |
Q3LI66
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A0A348FV93
F1D8N3
Q0PTK2
Q7LCB3
Q92731
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PDB IDs |
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1L2J
1NDE
1QKM
1U3Q
1U3R
1U3S
1U9E
1X76
1X78
1X7B
1X7J
1YY4
1YYE
1ZAF
2FSZ
2GIU
2I0G
2JJ3
2NV7
2QTU
2YJD
2YLY
2Z4B
3OLL
3OLS
3OMO
3OMP
3OMQ
4J24
4J26
4ZI1
5TOA
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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