IK and FANCC

Data Source:
BioGRID (two hybrid)

		IK	FANCC
Description		IK cytokine	FA complementation group C
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Speck U2-type Precatalytic Spliceosome Mitotic Spindle Pole	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle MRNA Splicing, Via Spliceosome Mitotic Spindle Assembly Checkpoint Viral Process Protein Localization To Kinetochore	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Germ Cell Development Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Interstrand Cross-link Repair Brain Morphogenesis Protein-containing Complex Assembly Neuronal Stem Cell Population Maintenance
Pathways			Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases			Fanconi anemia
GWAS		Schizophrenia ( 29483656) Serum immune biomarker levels ( 32066700)	Birth weight ( 31043758) Hematocrit ( 32888494) Offspring birth weight ( 31043758) Polycystic ovary syndrome ( 26284813)
Interacting Genes		26 interacting genes: APP CEP70 CHD3 CTNNBL1 DDX6 EGLN3 FANCC FRA10AC1 GRB2 KAT5 KDM1A MBD3 MFAP1 NUP62 PFN2 QARS1 RACK1 RBM10 SMU1 SUPT5H THOC1 TOE1 TRIM55 TRIM63 TTC14 ZCCHC10	54 interacting genes: APC AZIN1 BMPR1A BUB1 CAPN10 CCNA2 CCND1 CDK1 CTBP1 DLC1 DNAJB1 EGFR FANCA FANCD2 FANCE FANCF FANCG FBXW7 GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRAS KRT1 MEOX2 MLH3 MT-ATP6 MUTYH NRAS PDGFRL PIK3CA PMS2 POR PRDX3 PRPF31 PTPN12 PTPRJ RB1 RPL18 RPS3A SMAD4 SPTA1 SPTAN1 SRC STAT1 STMN1 STMN2 TCERG1 TGFBR2 USP14 ZBTB32
Entrez ID		3550	2176
HPRD ID		02771	01967
Ensembl ID		ENSG00000113141	ENSG00000158169
Uniprot IDs		Q13123 Q95HA6 Q9UK43	A0A024R9N2 A0A087WW44 B4E3W2 Q00597
PDB IDs		5O9Z 6Q8I
Enriched GO Terms of Interacting Partners?
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