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FANCC and CAPN10
Data Source:
BioGRID
(two hybrid)
FANCC
CAPN10
Description
FA complementation group C
calpain 10
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Fanconi Anaemia Nuclear Complex
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Molecular Function
Protein Binding
SNARE Binding
Calcium-dependent Cysteine-type Endopeptidase Activity
Protein Binding
Cytoskeletal Protein Binding
Biological Process
Myeloid Cell Homeostasis
DNA Repair
Nucleotide-excision Repair
Germ Cell Development
Removal Of Superoxide Radicals
Cellular Response To Oxidative Stress
Interstrand Cross-link Repair
Brain Morphogenesis
Protein-containing Complex Assembly
Neuronal Stem Cell Population Maintenance
Proteolysis
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Actin Cytoskeleton Reorganization
Positive Regulation Of Insulin Secretion
Positive Regulation Of Intracellular Transport
Cellular Response To Insulin Stimulus
Positive Regulation Of Glucose Import
Type B Pancreatic Cell Apoptotic Process
Positive Regulation Of Type B Pancreatic Cell Apoptotic Process
Pathways
Fanconi Anemia Pathway
TP53 Regulates Transcription of DNA Repair Genes
Degradation of the extracellular matrix
Drugs
Diseases
Fanconi anemia
Type II diabetes mellitus
GWAS
Birth weight (
31043758
)
Hematocrit (
32888494
)
Offspring birth weight (
31043758
)
Polycystic ovary syndrome (
26284813
)
Interacting Genes
54 interacting genes:
APC
AZIN1
BMPR1A
BUB1
CAPN10
CCNA2
CCND1
CDK1
CTBP1
DLC1
DNAJB1
EGFR
FANCA
FANCD2
FANCE
FANCF
FANCG
FBXW7
GSTP1
HSP90AA1
HSP90B1
HSPA1A
HSPA4
HSPA8
IK
KRAS
KRT1
MEOX2
MLH3
MT-ATP6
MUTYH
NRAS
PDGFRL
PIK3CA
PMS2
POR
PRDX3
PRPF31
PTPN12
PTPRJ
RB1
RPL18
RPS3A
SMAD4
SPTA1
SPTAN1
SRC
STAT1
STMN1
STMN2
TCERG1
TGFBR2
USP14
ZBTB32
5 interacting genes:
EFNB1
FANCC
FLOT1
PSMA7
SHD
Entrez ID
2176
11132
HPRD ID
01967
05595
Ensembl ID
ENSG00000158169
ENSG00000142330
Uniprot IDs
A0A024R9N2
A0A087WW44
B4E3W2
Q00597
Q9HC96
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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