IK and TOE1

		IK	TOE1
Description		IK cytokine	target of EGR1, exonuclease
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GO Annotations	Cellular Component	Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Speck U2-type Precatalytic Spliceosome Mitotic Spindle Pole	Nucleoplasm Nucleolus Cytoplasm Cajal Body Nuclear Body Nuclear Speck
	Molecular Function	Protein Binding Identical Protein Binding	3'-5'-exoribonuclease Activity RNA Binding Poly(A)-specific Ribonuclease Activity Protein Binding SnRNA Binding Metal Ion Binding
	Biological Process	Mitotic Cell Cycle MRNA Splicing, Via Spliceosome Mitotic Spindle Assembly Checkpoint Viral Process Protein Localization To Kinetochore	SnRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways
Drugs
Diseases
GWAS		Schizophrenia ( 29483656) Serum immune biomarker levels ( 32066700)
Interacting Genes		26 interacting genes: APP CEP70 CHD3 CTNNBL1 DDX6 EGLN3 FANCC FRA10AC1 GRB2 KAT5 KDM1A MBD3 MFAP1 NUP62 PFN2 QARS1 RACK1 RBM10 SMU1 SUPT5H THOC1 TOE1 TRIM55 TRIM63 TTC14 ZCCHC10	25 interacting genes: ABCF3 AGGF1 AP2A1 APLP1 CA12 HNRNPF IK IL7R LSM4 PPP1CA PRCC RAB40C RBM39 RBM8A RPS3A SF3B2 SF3B3 SH3GL3 SQSTM1 SRSF6 SUMO1 U2AF1 UNC13B WDR77 WDR83
Entrez ID		3550	114034
HPRD ID		02771	18212
Ensembl ID		ENSG00000113141	ENSG00000132773
Uniprot IDs		Q13123 Q95HA6 Q9UK43	Q96GM8
PDB IDs		5O9Z 6Q8I	2FC6
Enriched GO Terms of Interacting Partners?
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