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FANCC and BMPR1A
Data Source:
BioGRID
(two hybrid)
FANCC
BMPR1A
Description
FA complementation group C
bone morphogenetic protein receptor type 1A
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Fanconi Anaemia Nuclear Complex
Plasma Membrane
Caveola
External Side Of Plasma Membrane
Integral Component Of Membrane
Dendrite
Neuronal Cell Body
Receptor Complex
HFE-transferrin Receptor Complex
Molecular Function
Protein Binding
Protein Serine/threonine Kinase Activity
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Transforming Growth Factor Beta Receptor Activity, Type I
Protein Binding
ATP Binding
Protein Homodimerization Activity
SMAD Binding
Metal Ion Binding
BMP Receptor Activity
Biological Process
Myeloid Cell Homeostasis
DNA Repair
Nucleotide-excision Repair
Germ Cell Development
Removal Of Superoxide Radicals
Cellular Response To Oxidative Stress
Interstrand Cross-link Repair
Brain Morphogenesis
Protein-containing Complex Assembly
Neuronal Stem Cell Population Maintenance
In Utero Embryonic Development
Mesoderm Formation
Somitogenesis
Mullerian Duct Regression
Positive Regulation Of Mesenchymal Cell Proliferation
Chondrocyte Differentiation
Outflow Tract Septum Morphogenesis
Outflow Tract Morphogenesis
Cardiac Conduction System Development
Mitral Valve Morphogenesis
Tricuspid Valve Morphogenesis
Endocardial Cushion Morphogenesis
Cardiac Right Ventricle Morphogenesis
Ventricular Trabecula Myocardium Morphogenesis
Ventricular Compact Myocardium Morphogenesis
Endocardial Cushion Formation
Protein Phosphorylation
Immune Response
Transforming Growth Factor Beta Receptor Signaling Pathway
Ectoderm Development
Dorsal/ventral Axis Specification
Dorsal/ventral Pattern Formation
Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Neural Crest Cell Development
Negative Regulation Of Smooth Muscle Cell Migration
Stem Cell Population Maintenance
Pituitary Gland Development
Neural Plate Mediolateral Regionalization
Lung Development
Positive Regulation Of Bone Mineralization
BMP Signaling Pathway
Hindlimb Morphogenesis
Dorsal Aorta Morphogenesis
Odontogenesis Of Dentin-containing Tooth
Embryonic Digit Morphogenesis
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Paraxial Mesoderm Structural Organization
Lateral Mesoderm Development
Regulation Of Lateral Mesodermal Cell Fate Specification
Mesendoderm Development
Embryonic Organ Development
Developmental Growth
Positive Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Neurogenesis
Roof Of Mouth Development
Regulation Of Cardiac Muscle Cell Proliferation
Positive Regulation Of Cardiac Muscle Cell Proliferation
Positive Regulation Of SMAD Protein Signal Transduction
Heart Formation
BMP Signaling Pathway Involved In Heart Development
Pharyngeal Arch Artery Morphogenesis
Cellular Response To Growth Factor Stimulus
Cellular Response To BMP Stimulus
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Positive Regulation Of Cardiac Ventricle Development
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Fibrous Ring Of Heart Morphogenesis
Regulation Of Neural Crest Cell Differentiation
Regulation Of Cellular Senescence
Pathways
Fanconi Anemia Pathway
TP53 Regulates Transcription of DNA Repair Genes
Signaling by BMP
Drugs
Dibotermin alfa
Diseases
Fanconi anemia
Hereditary mixed polyposis syndrome
Juvenile polyposis syndrome
GWAS
Birth weight (
31043758
)
Hematocrit (
32888494
)
Offspring birth weight (
31043758
)
Polycystic ovary syndrome (
26284813
)
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Refractive error (
32231278
)
White blood cell count (
32888494
)
Interacting Genes
54 interacting genes:
APC
AZIN1
BMPR1A
BUB1
CAPN10
CCNA2
CCND1
CDK1
CTBP1
DLC1
DNAJB1
EGFR
FANCA
FANCD2
FANCE
FANCF
FANCG
FBXW7
GSTP1
HSP90AA1
HSP90B1
HSPA1A
HSPA4
HSPA8
IK
KRAS
KRT1
MEOX2
MLH3
MT-ATP6
MUTYH
NRAS
PDGFRL
PIK3CA
PMS2
POR
PRDX3
PRPF31
PTPN12
PTPRJ
RB1
RPL18
RPS3A
SMAD4
SPTA1
SPTAN1
SRC
STAT1
STMN1
STMN2
TCERG1
TGFBR2
USP14
ZBTB32
45 interacting genes:
ACVR1
ALDOB
AOPEP
BAMBI
BMP2
BMP4
BMP5
BMP6
BMP7
BMPR1B
BMPR2
CDK8
CTSV
FANCC
FBP1
FBP2
FKBP1A
FKBP1B
GALNT12
GDF5
GDF6
GDF9
HOXC8
HRAS
IGFBP3
MAP2K1
MSANTD3
NEDD4
NEDD4L
OTUB1
RASA1
SEC61B
SF3B4
SFRP2
SFRP4
SMAD1
TAB1
TDGF1
TGFB1
TGFBRAP1
TRMO
USP15
XPA
ZMYND11
ZNF189
Entrez ID
2176
657
HPRD ID
01967
03192
Ensembl ID
ENSG00000158169
ENSG00000107779
Uniprot IDs
A0A024R9N2
A0A087WW44
B4E3W2
Q00597
P36894
PDB IDs
1ES7
1REW
2GOO
2H62
2H64
2K3G
2QJ9
2QJA
2QJB
3NH7
3QB4
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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