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APOD and GJA8
Data Source:
BioGRID
(two hybrid)
APOD
GJA8
Description
apolipoprotein D
gap junction protein alpha 8
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Endoplasmic Reticulum
Cytosolic Ribosome
Dendrite
Neuronal Cell Body
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Integral Component Of Plasma Membrane
Connexin Complex
Molecular Function
Lipid Transporter Activity
Protein Binding
Cholesterol Binding
Gap Junction Channel Activity
Protein Binding
Identical Protein Binding
Biological Process
Response To Reactive Oxygen Species
Angiogenesis
Glucose Metabolic Process
Lipid Metabolic Process
Lipid Transport
Brain Development
Aging
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Peripheral Nervous System Axon Regeneration
Tissue Regeneration
Negative Regulation Of Protein Import Into Nucleus
Response To Drug
Negative Regulation Of Smooth Muscle Cell Proliferation
Response To Axon Injury
Negative Regulation Of Focal Adhesion Assembly
Negative Regulation Of Lipoprotein Lipid Oxidation
Negative Regulation Of Monocyte Chemotactic Protein-1 Production
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Smooth Muscle Cell-matrix Adhesion
Negative Regulation Of T Cell Migration
Lens Development In Camera-type Eye
Cell-cell Signaling
Transmembrane Transport
Gap Junction-mediated Intercellular Transport
Pathways
Transport of fatty acids
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Gap junction assembly
Drugs
Vitamin A
Copper
Diseases
GWAS
HDL cholesterol levels (
32203549
)
Retinopathy x type 2 diabetes interaction (
32541925
)
Interacting Genes
51 interacting genes:
AIG1
APH1A
APOA2
AQP9
ATP6V0B
ATP6V0E1
BCL2L13
BIK
CD53
CD79A
CLDN7
CLEC10A
CPLX4
CREB3
CREB3L1
ERGIC3
EVI2B
FAM209A
FFAR2
FKBP7
FPR2
GDAP1
GJA8
GORAB
GPR151
GPR42
GPX8
KCNJ6
KIR2DL3
LEPR
LMNA
MFF
MGST3
MTERF2
MTIF3
NCAPH2
PDZK1IP1
POLR2M
RHBDL1
SHBG
SIGLECL1
SLC10A6
SLC35C2
TEX29
TMEM237
TMEM31
TMEM45B
TMEM52B
TMEM79
VAPA
VSIR
121 interacting genes:
ABL1
ACKR2
APOA2
APOD
APOL3
AQP4
ARL6IP6
ATP6V0B
C1GALT1
C2CD2L
C3orf52
CCDC167
CCL4
CD53
CIAO2A
CLDN19
CLDN4
CLEC1A
CLN6
COX20
CTXN3
CXCL16
CYBC1
CYP4F2
DEFB121
DOLK
ERMP1
FDFT1
FXYD6
GIMAP1
GIMAP5
GJB2
GPR108
GPR151
GPR61
GUCA2A
IGFBP5
INSIG2
ITGAM
KIR2DL3
LAPTM4B
LAT
LEPROTL1
LHFPL5
MAL
MALL
MARCHF2
MFSD11
MFSD6
MGST2
MIP
MS4A13
ORMDL2
OTOP2
P2RY13
PGAP2
PLN
PMP22
PNLIPRP1
PRAF2
PROKR2
PTPRN
QRFPR
REEP6
RNF152
RUSF1
RXFP4
S1PR5
SCARF1
SEC22B
SEC22C
SEC23A
SFTPC
SLC13A2
SLC13A5
SLC16A12
SLC16A13
SLC16A3
SLC30A3
SLC35A4
SLC35F1
SLC35F6
SLC38A4
SLC38A7
SLC39A2
SLC39A7
SLC39A9
SLC52A1
SLC66A1
SLC66A2
SLC8A3
SMCO4
SMIM1
STX1B
STX8
THSD7B
TJP1
TMBIM6
TMEM100
TMEM107
TMEM121
TMEM128
TMEM147
TMEM182
TMEM239
TMEM242
TMEM243
TMEM42
TMEM45A
TMEM60
TMEM65
TMEM72
TMEM86B
TSPAN33
TWSG1
UBXN8
UNC93A
UPK1B
VAMP5
YIF1A
YIPF6
Entrez ID
347
2703
HPRD ID
00134
02939
Ensembl ID
ENSG00000189058
ENSG00000121634
Uniprot IDs
P05090
P48165
X5D7G1
PDB IDs
2APD
2HZQ
2HZR
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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