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APOD and APOA2
Data Source:
HPRD
(in vitro)
APOD
APOA2
Description
apolipoprotein D
apolipoprotein A2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Endoplasmic Reticulum
Cytosolic Ribosome
Dendrite
Neuronal Cell Body
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Extracellular Region
Early Endosome
Endoplasmic Reticulum Lumen
Cytosol
Very-low-density Lipoprotein Particle
High-density Lipoprotein Particle
Spherical High-density Lipoprotein Particle
Chylomicron
Extracellular Exosome
Blood Microparticle
Molecular Function
Lipid Transporter Activity
Protein Binding
Cholesterol Binding
Signaling Receptor Binding
Lipid Transporter Activity
Protein Binding
Phospholipid Binding
High-density Lipoprotein Particle Binding
Lipid Binding
Cholesterol Binding
Heat Shock Protein Binding
Phosphatidylcholine Binding
Apolipoprotein Receptor Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Lipase Inhibitor Activity
Phosphatidylcholine-sterol O-acyltransferase Activator Activity
High-density Lipoprotein Particle Receptor Binding
Cholesterol Transfer Activity
Biological Process
Response To Reactive Oxygen Species
Angiogenesis
Glucose Metabolic Process
Lipid Metabolic Process
Lipid Transport
Brain Development
Aging
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Peripheral Nervous System Axon Regeneration
Tissue Regeneration
Negative Regulation Of Protein Import Into Nucleus
Response To Drug
Negative Regulation Of Smooth Muscle Cell Proliferation
Response To Axon Injury
Negative Regulation Of Focal Adhesion Assembly
Negative Regulation Of Lipoprotein Lipid Oxidation
Negative Regulation Of Monocyte Chemotactic Protein-1 Production
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Smooth Muscle Cell-matrix Adhesion
Negative Regulation Of T Cell Migration
Retinoid Metabolic Process
Negative Regulation Of Cytokine Production Involved In Immune Response
Triglyceride Metabolic Process
Phosphatidylcholine Biosynthetic Process
Cholesterol Metabolic Process
Phospholipid Catabolic Process
Response To Glucose
Positive Regulation Of Cholesterol Esterification
Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling
Viral Process
Protein Oxidation
Peptidyl-methionine Modification
Regulation Of Lipid Metabolic Process
Cholesterol Transport
Regulation Of Protein Stability
Negative Regulation Of Cholesterol Transport
Positive Regulation Of Interleukin-8 Production
Cholesterol Efflux
Phospholipid Efflux
Triglyceride-rich Lipoprotein Particle Remodeling
Chylomicron Remodeling
Low-density Lipoprotein Particle Remodeling
High-density Lipoprotein Particle Remodeling
Chylomicron Assembly
High-density Lipoprotein Particle Assembly
High-density Lipoprotein Particle Clearance
Lipoprotein Metabolic Process
Cholesterol Homeostasis
Post-translational Protein Modification
Reverse Cholesterol Transport
Cellular Protein Metabolic Process
Diacylglycerol Catabolic Process
Positive Regulation Of Phagocytosis
Protein Stabilization
Negative Regulation Of Lipid Catabolic Process
Positive Regulation Of Lipid Catabolic Process
Negative Regulation Of Lipase Activity
Negative Regulation Of Cholesterol Import
Negative Regulation Of Cholesterol Transporter Activity
Intermembrane Lipid Transfer
Pathways
Transport of fatty acids
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
PPARA activates gene expression
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Chylomicron assembly
Chylomicron remodeling
Retinoid metabolism and transport
Retinoid metabolism and transport
Drugs
Vitamin A
Copper
Zinc
Copper
Zinc acetate
Diseases
Familial amyloidosis
GWAS
HDL cholesterol levels (
32203549
)
Interacting Genes
51 interacting genes:
AIG1
APH1A
APOA2
AQP9
ATP6V0B
ATP6V0E1
BCL2L13
BIK
CD53
CD79A
CLDN7
CLEC10A
CPLX4
CREB3
CREB3L1
ERGIC3
EVI2B
FAM209A
FFAR2
FKBP7
FPR2
GDAP1
GJA8
GORAB
GPR151
GPR42
GPX8
KCNJ6
KIR2DL3
LEPR
LMNA
MFF
MGST3
MTERF2
MTIF3
NCAPH2
PDZK1IP1
POLR2M
RHBDL1
SHBG
SIGLECL1
SLC10A6
SLC35C2
TEX29
TMEM237
TMEM31
TMEM45B
TMEM52B
TMEM79
VAPA
VSIR
31 interacting genes:
ABCA13
APOA1
APOC1
APOD
APOF
AQP6
C4A
CATSPER1
CIAO2A
CREB3
CYBC1
GET1
GJA8
HSD17B13
KIR2DL3
LMNA
MUC1
NAXE
NDRG1
PANX1
PDZK1IP1
PLTP
PSCA
SCARB1
SLC7A1
SSMEM1
STOM
TMEM45A
TMEM82
TREM2
VKORC1
Entrez ID
347
336
HPRD ID
00134
00129
Ensembl ID
ENSG00000189058
ENSG00000158874
Uniprot IDs
P05090
P02652
PDB IDs
2APD
2HZQ
2HZR
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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