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HSD17B13 and FATE1
Data Source:
BioGRID
(two hybrid)
HSD17B13
FATE1
Description
hydroxysteroid 17-beta dehydrogenase 13
fetal and adult testis expressed 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Lipid Droplet
Cytosol
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Mitochondria-associated Endoplasmic Reticulum Membrane
Molecular Function
Molecular_function
Protein Binding
Steroid Dehydrogenase Activity
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Protein Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Biological Process
Lipid Droplet Organization
Positive Regulation Of Lipid Biosynthetic Process
Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Mitochondrial Calcium Ion Concentration
Pathways
Lipid particle organization
Drugs
Diseases
GWAS
Bulimia nervosa (
23568457
)
Liver enzyme levels (alanine transaminase) (
22001757
)
Nonalcoholic steatohepatitis (
32298765
)
Platelet count (
22139419
)
Rosacea symptom severity (
29771307
)
Triglyceride levels (
31928498
)
Systemising (
31508503
)
Interacting Genes
118 interacting genes:
ABHD16A
ADGRE2
AGPAT3
AGPAT4
AGTRAP
AIG1
ANKRD46
AOC3
APOA2
ARL6IP1
ATP6V0C
BBC3
BRICD5
C3orf52
CACNG1
CALHM6
CCDC167
CDIPT
CLDN10
CLDN19
CLDN4
CLDND2
CMTM5
CMTM7
CYB5R3
CYBC1
CYP4F2
DIABLO
EBP
ECPAS
FATE1
FAXDC2
FETUB
GJB2
GOLM1
GOSR2
GYPB
HSD3B7
IGFBP5
INSIG2
ITGAM
JAGN1
LPCAT2
LRAT
MARCHF5
MFSD5
MGLL
MIEF2
MMP14
MOSPD3
MS4A1
NAPB
NAT8
NRM
ORMDL3
PBX3
PLIN3
PLN
PLP2
PNLIPRP1
PTPN9
RABAC1
REEP6
RHOU
RPRM
RUSF1
SACM1L
SCAMP5
SCARF1
SCD
SEC22B
SERP1
SFT2D2
SFXN1
SFXN2
SFXN3
SLC25A46
SLC30A3
SLC35B4
SLC35E4
SMIM1
SNORC
SPG21
ST6GAL2
STRIT1
STX5
STX7
TBRG4
TF
THSD7A
TIMM23
TIMMDC1
TMEM100
TMEM120A
TMEM140
TMEM14C
TMEM167B
TMEM19
TMEM203
TMEM222
TMEM229B
TMEM243
TMEM255B
TMEM31
TMEM42
TMEM60
TMEM86B
TMEM97
TMX2
TPRG1
TREX1
UBXN8
UNC50
VAMP2
VAPA
VAPB
YIPF2
YIPF4
99 interacting genes:
AGTRAP
APOL3
AQP9
ASGR2
ATCAY
BCL2L2
BIK
BNIP2
BNIP3
BNIP3L
BSND
BTN2A2
C1QL4
CALN1
CCDC70
CD302
CD79A
CD83
CDC37
CERS4
CREB3L3
CSF2RA
CTRL
CXCR1
CXCR3
DCTN5
DNAJC30
EMD
FAM177A1
FAM209A
FRMD8
GIMAP5
GINM1
GOSR2
GPR25
HSD17B13
INPP5K
KASH5
KCNS2
LMNA
LNPEP
LRRC25
MARCHF2
MARCHF3
MARCHF5
MARVELD2
MFF
MOSPD3
MR1
NDUFB11
NRG4
NRSN1
OCLN
OTOP2
PIN4
PKMYT1
PLP2
PRRG2
RBFA
RIC3
RNF183
RPRM
RTP2
SCAMP5
SEC22A
SEC22C
SEC23A
SEC23B
SLC38A1
SLC41A2
SLC7A1
SLC7A14
SMIM14
SNAP47
SSMEM1
SYNDIG1
SYNE4
SYNGR1
SYNGR2
SYNPR
TBP
TIMMDC1
TM4SF4
TMEM11
TMEM179B
TMEM201
TMEM74
TRAF2
TRAF3IP3
UBE2I
UNC93B1
USHBP1
USP20
VSIG4
VSTM1
YIPF2
YIPF4
ZCCHC12
ZFPL1
Entrez ID
345275
89885
HPRD ID
18023
02346
Ensembl ID
ENSG00000170509
ENSG00000147378
Uniprot IDs
Q7Z5P4
Q969F0
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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