FATE1 and CSF2RA

Data Source:
BioGRID (two hybrid)

		FATE1	CSF2RA
Description		fetal and adult testis expressed 1	colony stimulating factor 2 receptor subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondria-associated Endoplasmic Reticulum Membrane	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Receptor Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding	Cytokine Receptor Activity Protein Binding Cytokine Binding Signaling Receptor Activity
	Biological Process	Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration	MAPK Cascade Cytokine-mediated Signaling Pathway Cellular Protein Metabolic Process
Pathways			Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Surfactant metabolism Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4 Interleukin receptor SHC signaling
Drugs			Sargramostim KB002 Regramostim Foreskin fibroblast (neonatal) Foreskin keratinocyte (neonatal) Clove oil
Diseases
GWAS		Systemising ( 31508503)	Schizophrenia ( 17522711)
Interacting Genes		99 interacting genes: AGTRAP APOL3 AQP9 ASGR2 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 C1QL4 CALN1 CCDC70 CD302 CD79A CD83 CDC37 CERS4 CREB3L3 CSF2RA CTRL CXCR1 CXCR3 DCTN5 DNAJC30 EMD FAM177A1 FAM209A FRMD8 GIMAP5 GINM1 GOSR2 GPR25 HSD17B13 INPP5K KASH5 KCNS2 LMNA LNPEP LRRC25 MARCHF2 MARCHF3 MARCHF5 MARVELD2 MFF MOSPD3 MR1 NDUFB11 NRG4 NRSN1 OCLN OTOP2 PIN4 PKMYT1 PLP2 PRRG2 RBFA RIC3 RNF183 RPRM RTP2 SCAMP5 SEC22A SEC22C SEC23A SEC23B SLC38A1 SLC41A2 SLC7A1 SLC7A14 SMIM14 SNAP47 SSMEM1 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM179B TMEM201 TMEM74 TRAF2 TRAF3IP3 UBE2I UNC93B1 USHBP1 USP20 VSIG4 VSTM1 YIPF2 YIPF4 ZCCHC12 ZFPL1	9 interacting genes: CHUK CSF2 CSF2RB FATE1 IKBKB KIT LYN PIK3R1 RPSA
Entrez ID		89885	1438
HPRD ID		02346	02381
Ensembl ID		ENSG00000147378	ENSG00000198223
Uniprot IDs		Q969F0	P15509
PDB IDs			4NKQ 4RS1
Enriched GO Terms of Interacting Partners?
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