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FATE1 and OCLN
Data Source:
BioGRID
(two hybrid)
FATE1
OCLN
Description
fetal and adult testis expressed 1
occludin
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Mitochondria-associated Endoplasmic Reticulum Membrane
Lysosomal Membrane
Plasma Membrane
Cell-cell Junction
Bicellular Tight Junction
Integral Component Of Membrane
Apical Plasma Membrane
Apicolateral Plasma Membrane
Lateral Plasma Membrane
Cell Junction
Endocytic Vesicle
Cell Leading Edge
Cytoplasmic Vesicle
Protein-containing Complex
Tight Junction
Molecular Function
Protein Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Protein Binding
Protein Domain Specific Binding
Biological Process
Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Mitochondrial Calcium Ion Concentration
Negative Regulation Of Protein Phosphorylation
Positive Regulation Of Lamellipodium Assembly
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Regulation Of Glucose Transmembrane Transport
Positive Regulation Of Microtubule Polymerization
Maintenance Of Blood-brain Barrier
Cell-cell Junction Organization
Positive Regulation Of Glucose Import
Protein-containing Complex Assembly
Response To Interleukin-18
Bicellular Tight Junction Assembly
Cellular Response To Tumor Necrosis Factor
Positive Regulation Of Wound Healing
Protein Localization To Cell Leading Edge
Positive Regulation Of Blood-brain Barrier Permeability
Regulation Of Bicellular Tight Junction Assembly
Pathways
Apoptotic cleavage of cell adhesion proteins
RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
Band-like calcification with simplified gyration and polymicrogyria (BLC-PMG); Pseudo-TORCH syndrome
GWAS
Systemising (
31508503
)
Hand grip strength (Mahalanobis distance) (
32235003
)
Interleukin-18 levels (
27989323
)
Interacting Genes
99 interacting genes:
AGTRAP
APOL3
AQP9
ASGR2
ATCAY
BCL2L2
BIK
BNIP2
BNIP3
BNIP3L
BSND
BTN2A2
C1QL4
CALN1
CCDC70
CD302
CD79A
CD83
CDC37
CERS4
CREB3L3
CSF2RA
CTRL
CXCR1
CXCR3
DCTN5
DNAJC30
EMD
FAM177A1
FAM209A
FRMD8
GIMAP5
GINM1
GOSR2
GPR25
HSD17B13
INPP5K
KASH5
KCNS2
LMNA
LNPEP
LRRC25
MARCHF2
MARCHF3
MARCHF5
MARVELD2
MFF
MOSPD3
MR1
NDUFB11
NRG4
NRSN1
OCLN
OTOP2
PIN4
PKMYT1
PLP2
PRRG2
RBFA
RIC3
RNF183
RPRM
RTP2
SCAMP5
SEC22A
SEC22C
SEC23A
SEC23B
SLC38A1
SLC41A2
SLC7A1
SLC7A14
SMIM14
SNAP47
SSMEM1
SYNDIG1
SYNE4
SYNGR1
SYNGR2
SYNPR
TBP
TIMMDC1
TM4SF4
TMEM11
TMEM179B
TMEM201
TMEM74
TRAF2
TRAF3IP3
UBE2I
UNC93B1
USHBP1
USP20
VSIG4
VSTM1
YIPF2
YIPF4
ZCCHC12
ZFPL1
11 interacting genes:
CLEC7A
CSNK1A1
CSNK2A1
FATE1
GPX8
PTPN2
SNW1
SYNE4
TJP1
TNFAIP3
ULK1
Entrez ID
89885
100506658
HPRD ID
02346
Ensembl ID
ENSG00000147378
ENSG00000197822
Uniprot IDs
Q969F0
A8K3T2
Q16625
PDB IDs
1WPA
1XAW
3G7C
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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