HSD17B13 and LPCAT2

Data Source:
BioGRID (two hybrid)

		HSD17B13	LPCAT2
Description		hydroxysteroid 17-beta dehydrogenase 13	lysophosphatidylcholine acyltransferase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lipid Droplet Cytosol	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Stack Lipid Droplet Plasma Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor	1-acylglycerol-3-phosphate O-acyltransferase Activity Calcium Ion Binding Protein Binding 1-alkenylglycerophosphocholine O-acyltransferase Activity 1-acylglycerophosphocholine O-acyltransferase Activity 1-alkylglycerophosphocholine O-acetyltransferase Activity Plasmalogen Synthase Activity
	Biological Process	Lipid Droplet Organization Positive Regulation Of Lipid Biosynthetic Process	Platelet Activating Factor Biosynthetic Process Phosphatidylcholine Acyl-chain Remodeling Membrane Organization
Pathways		Lipid particle organization	Acyl chain remodelling of PC
Drugs
Diseases
GWAS		Bulimia nervosa ( 23568457) Liver enzyme levels (alanine transaminase) ( 22001757) Nonalcoholic steatohepatitis ( 32298765) Platelet count ( 22139419) Rosacea symptom severity ( 29771307) Triglyceride levels ( 31928498)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Thyroid hormone levels ( 23408906)
Interacting Genes		118 interacting genes: ABHD16A ADGRE2 AGPAT3 AGPAT4 AGTRAP AIG1 ANKRD46 AOC3 APOA2 ARL6IP1 ATP6V0C BBC3 BRICD5 C3orf52 CACNG1 CALHM6 CCDC167 CDIPT CLDN10 CLDN19 CLDN4 CLDND2 CMTM5 CMTM7 CYB5R3 CYBC1 CYP4F2 DIABLO EBP ECPAS FATE1 FAXDC2 FETUB GJB2 GOLM1 GOSR2 GYPB HSD3B7 IGFBP5 INSIG2 ITGAM JAGN1 LPCAT2 LRAT MARCHF5 MFSD5 MGLL MIEF2 MMP14 MOSPD3 MS4A1 NAPB NAT8 NRM ORMDL3 PBX3 PLIN3 PLN PLP2 PNLIPRP1 PTPN9 RABAC1 REEP6 RHOU RPRM RUSF1 SACM1L SCAMP5 SCARF1 SCD SEC22B SERP1 SFT2D2 SFXN1 SFXN2 SFXN3 SLC25A46 SLC30A3 SLC35B4 SLC35E4 SMIM1 SNORC SPG21 ST6GAL2 STRIT1 STX5 STX7 TBRG4 TF THSD7A TIMM23 TIMMDC1 TMEM100 TMEM120A TMEM140 TMEM14C TMEM167B TMEM19 TMEM203 TMEM222 TMEM229B TMEM243 TMEM255B TMEM31 TMEM42 TMEM60 TMEM86B TMEM97 TMX2 TPRG1 TREX1 UBXN8 UNC50 VAMP2 VAPA VAPB YIPF2 YIPF4	8 interacting genes: CREB3 EBP ERGIC3 HSD17B13 KCNJ6 MFSD14B RETREG3 RHBDD1
Entrez ID		345275	54947
HPRD ID		18023	07913
Ensembl ID		ENSG00000170509	ENSG00000087253
Uniprot IDs		Q7Z5P4	Q7L5N7
PDB IDs
Enriched GO Terms of Interacting Partners?
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