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CPLX4 and GAD2
Data Source:
BioGRID
(two hybrid)
CPLX4
GAD2
Description
complexin 4
glutamate decarboxylase 2
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
SNARE Complex
Terminal Bouton
Golgi Membrane
Cytosol
Plasma Membrane
Axon
Synaptic Vesicle Membrane
Anchored Component Of Membrane
Presynaptic Membrane
Perinuclear Region Of Cytoplasm
Inhibitory Synapse
Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
Molecular Function
SNARE Binding
Protein Binding
Syntaxin Binding
Glutamate Decarboxylase Activity
Protein Binding
Glutamate Binding
Pyridoxal Phosphate Binding
Protein-containing Complex Binding
Biological Process
Visual Perception
Synaptic Vesicle Exocytosis
Regulation Of Neurotransmitter Secretion
Response To Stimulus
Glutamate Decarboxylation To Succinate
Chemical Synaptic Transmission
Neurotransmitter Secretion
Neurotransmitter Biosynthetic Process
Response To Drug
Pathways
GABA synthesis
GABA synthesis, release, reuptake and degradation
MECP2 regulates transcription of genes involved in GABA signaling
Drugs
Pyridoxal phosphate
Glutamic acid
Diseases
GWAS
Cardiac troponin-I levels (
31014085
)
Chronotype (
27494321
)
Macular thickness (
30535121
)
Morning vs. evening chronotype (
27494321
)
Lean body mass (
28552196
)
Interacting Genes
92 interacting genes:
ADIPOQ
AGTRAP
AIG1
AOC3
APOD
AQP1
AQP9
ASGR1
ATP6V0C
BNIP2
C14orf180
C1GALT1
C3orf52
C5
CACNG1
CCL4L2
CD81
CDIPT
CDS2
CLDND2
CLEC4G
CLN6
CMTM5
CNIH1
CTSA
CTXN3
CYB5B
CYBC1
CYP4F2
DEFB127
EMD
GAD2
GIMAP1
GRM2
HACD1
HHATL
HMOX1
INSIG2
LPAR3
MAL
MALL
MAN2B2
MGAM
NINJ2
NRM
ORMDL1
PGAP2
PLN
PLP2
PLPP4
PNLIPRP1
PTPN9
RTP2
SEC22B
SELENOK
SFTPC
SLC30A2
SLC30A8
SLC35A1
SLC35A4
SLC35B4
SLC38A7
SLC39A9
SMCO4
STX3
STX8
SYNJ2BP
TF
TMEM120B
TMEM14A
TMEM14B
TMEM19
TMEM201
TMEM203
TMEM218
TMEM229B
TMEM243
TMEM254
TMEM267
TMEM60
TMEM79
TMEM86A
TMEM97
TRAF3IP3
TSPO2
UBIAD1
VAMP4
VAMP5
VKORC1
WFDC2
YIPF6
ZFPL1
45 interacting genes:
ABHD5
AGTRAP
APOC2
APOC4
ARL13B
ARL6IP1
ARMC12
BSND
CACNG1
CMTM5
CPLX4
CYB561D1
DERL1
DERL3
DGAT2L6
DMKN
F10
FADS6
FAM114A2
FAM163A
GAD1
HIGD1C
LIME1
MAL2
MEST
MRM3
PBX3
PLIN3
PRKACA
PRKCE
RDH10
RHEX
RPRM
SCAMP1
SDR16C5
SEC22A
SMPD2
SPG21
SYCE2
SYNGR3
TMEM120B
TMEM128
TMEM159
TNFRSF10D
TSPAN33
Entrez ID
339302
2572
HPRD ID
13091
11817
Ensembl ID
ENSG00000166569
ENSG00000136750
Uniprot IDs
Q7Z7G2
Q05329
Q5VZ30
PDB IDs
1ES0
2OKK
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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